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Coronavirus research highlights

A novel coronavirus, 2019-nCoV, has been identified as the cause of an outbreak of respiratory illness that originated in Wuhan, China, and which has spread to several other countries around the world.  Recent content from BMC and SpringerOpen journals relevant to coronavirus research, as well as additional commentary on this topic, is included below. 

BMC, as part of Springer Nature, encourages early sharing of research submitted to all our journals through preprints, and our In Review preprint service is available for many journals. We strongly urge authors submitting articles related to this emergency to BMC journals to share underlying interim and final research datasets relating to the outbreak as rapidly and widely as possible, including with public health and research communities and the WHO.

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  1. Patients with rheumatoid arthritis (RA) represent one of the fragile patient groups that might be susceptible to the critical form of the coronavirus disease − 19 (COVID-19). On the other side, RA patients hav...

    Authors: Mahmood Y. Hachim, Ibrahim Y. Hachim, Kashif Bin Naeem, Haifa Hannawi, Issa Al Salmi and Suad Hannawi

    Citation: Translational Medicine Communications 2020 5:14

    Content type: Research

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  2. Whilst the issues around early termination of randomised controlled trials (RCTs) are well documented in the literature, trials can also be temporarily suspended with the real prospect that they may subsequent...

    Authors: Lynda Constable, Tracey Davidson, Suzanne Breeman, Seonaidh Cotton, Alison McDonald, Samantha Wileman and John Norrie

    Citation: Trials 2020 21:765

    Content type: Commentary

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  3. Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spreads rapidly and has attracted worldwide attention.

    Authors: Shuo Jiang, Qiuyue Li, Chaoqun Li, Shanshan Liu, Xiaomeng He, Tao Wang, Hua Li, Christopher Corpe, Xiaoyan Zhang, Jianqing Xu and Jin Wang

    Citation: Journal of Translational Medicine 2020 18:345

    Content type: Research

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  4. Coronavirus is challenging the global health care system from time to time. The pregnant state, with alterations in hormone levels and decreased lung volumes due to a gravid uterus and slightly immunocompromis...

    Authors: Kuma Diriba, Ephrem Awulachew and Eyob Getu

    Citation: European Journal of Medical Research 2020 25:39

    Content type: Review

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  5. Coronavirus disease 2019 outbreak is the first reported case in Wuhan, China in December 2019 and suddenly became a major global health concern. According to the European Centre for Disease Prevention and Cont...

    Authors: Abrha Hailay, Woldu Aberhe, Kidane Zereabruk, Guesh Mebrahtom, Teklehaimanot Haile, Degena Bahrey and Teklewoini Mariye

    Citation: Asthma Research and Practice 2020 6:8

    Content type: Research

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  6. “Immune boosting” is a trending topic during the COVID-19 pandemic. The concept of “immune boosting” is scientifically misleading and often used to market unproven products and therapies. This paper presents a...

    Authors: Darren N. Wagner, Alessandro R. Marcon and Timothy Caulfield

    Citation: Allergy, Asthma & Clinical Immunology 2020 16:76

    Content type: Letter to the editor

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  7. Severe acute respiratory syndrome CoV-2 (SARS-CoV-2) caused the first coronavirus disease 2019 (COVID-19) outbreak in China and has become a public health emergency of international concern. SARS-CoV-2 outbrea...

    Authors: Maria Pachetti, Bruna Marini, Fabiola Giudici, Francesca Benedetti, Silvia Angeletti, Massimo Ciccozzi, Claudio Masciovecchio, Rudy Ippodrino and Davide Zella

    Citation: Journal of Translational Medicine 2020 18:338

    Content type: Research

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  8. Quarantine/confinement is an effective measure to face the Coronavirus disease 2019 (COVID-19). Consequently, in response to this stressful situation, people confined to their homes may change their everyday e...

    Authors: Chadia Haddad, Maha Zakhour, Maria Bou kheir, Rima Haddad, Myriam Al Hachach, Hala Sacre and Pascale Salameh

    Citation: Journal of Eating Disorders 2020 8:40

    Content type: Research article

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  9. The new Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which was first detected in Wuhan (China) in December of 2019 is responsible for the current global pandemic. Phylogenetic analysis reveale...

    Authors: Francesca Benedetti, Greg A. Snyder, Marta Giovanetti, Silvia Angeletti, Robert C. Gallo, Massimo Ciccozzi and Davide Zella

    Citation: Journal of Translational Medicine 2020 18:329

    Content type: Research

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  10. Patients with severe Coronavirus Disease 2019 (COVID-19) will progress rapidly to acute respiratory failure or death. We aimed to develop a quantitative tool for early predicting mortality risk of patients wit...

    Authors: Zhihong Weng, Qiaosen Chen, Sumeng Li, Huadong Li, Qian Zhang, Sihong Lu, Li Wu, Leiqun Xiong, Bobin Mi, Di Liu, Mengji Lu, Dongliang Yang, Hongbo Jiang, Shaoping Zheng and Xin Zheng

    Citation: Journal of Translational Medicine 2020 18:328

    Content type: Research

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  11. In December 2019, pneumonia associated with the 2019 novel coronavirus (COVID-19) emerged in Wuhan, China. The number of cases has increased rapidly. Patients with severe disease have a poor prognosis, and the...

    Authors: Shuaipan Zhang, Qingguang Zhu, Chao Zhan, Wei Cheng, Xiao Mingfang, Min Fang and Lei Fang

    Citation: Trials 2020 21:751

    Content type: Study protocol

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  12. The first case of a coronavirus 2019 (COVID-19) infection in a Sri Lankan was reported on March 11, 2020. The situation in Sri Lanka changed with the rapid increase of personnel contracting COVID-19 in a naval...

    Authors: Madunil A. Niriella, Dileepa S. Ediriweera, Arjuna P. De Silva, Ranjan Premarathne, Priyantha Balasooriya, Kaluthanthri D. Duminda, Neelika G. Malavige, Kamani Wanigasuriya, Sarath Lekamwasam, Senanayake A. Kularathne, Sisira Siribaddana, Hithanadura J. de Silva and Saroj Jayasinghe

    Citation: Trials 2020 21:748

    Content type: Study protocol

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  13. Within two decades, there have emerged three highly pathogenic and deadly human coronaviruses, namely SARS-CoV, MERS-CoV and SARS-CoV-2. The economic burden and health threats caused by these coronaviruses are...

    Authors: Zhixing Zhu, Xihua Lian, Xiaoshan Su, Weijing Wu, Giuseppe A. Marraro and Yiming Zeng

    Citation: Respiratory Research 2020 21:224

    Content type: Review

    Published on:

  14. COVID-19 is characterized by fast deterioration in the mechanism of cytokine storm. Therefore, treatment with immunomodulating agents should be initiated as soon as hyperinflammation is established. Evidence f...

    Authors: Regina B. Podlasin, Justyna D. Kowalska, Andrzej Pihowicz, Beata Wojtycha-Kwaśnica, Magdalena Thompson, Tomasz Dyda, Hanna Czeszko-Paprocka and Andrzej Horban

    Citation: European Journal of Medical Research 2020 25:37

    Content type: Case report

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  15. The coronavirus disease 2019 (COVID-19) pandemic has led to a declaration of a Public Health Emergency of International Concern by the World Health Organization. As of May 18, 2020, there have been more than 4...

    Authors: Yi Xu, David J. Baylink, Chien-Shing Chen, Mark E. Reeves, Jeffrey Xiao, Curtis Lacy, Eric Lau and Huynh Cao

    Citation: Journal of Translational Medicine 2020 18:322

    Content type: Review

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  16. This study aims to determine the protection provided by Shenfu injection (a traditional Chinese medicine) against development of organ dysfunction in critically ill patients with coronavirus disease 2019 (COVI...

    Authors: Zong-Yu Wang, Shou-Zhi Fu, Liang Xu, Shu-Sheng Li, Ke-Jian Qian, Xian-Di He, Guo-Chao Zhu, Liang-Hai Li, Jun Zhang, Wen-Fang Li, Bing-Yu Qin, Chen-Liang Zhou and Peng-Lin Ma

    Citation: Trials 2020 21:738

    Content type: Letter

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  17. Novel coronavirus disease 2019 presents with fever, dry cough, fatigue, and shortness of breath in most cases; however, some rare manifestations in other organs have also been reported so far.

    Authors: Maryam Heidarpour, Mehrbod Vakhshoori, Saeed Abbasi, Davood Shafie and Nima Rezaei

    Citation: Journal of Medical Case Reports 2020 14:134

    Content type: Case report

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  18. In December 2019, an outbreak of coronavirus disease (later named as COVID-19) was identified in Wuhan, China and, later on, detected in other parts of China. Our aim is to evaluate the effectiveness of the ev...

    Authors: Hui Wan, Jing-An Cui and Guo-Jing Yang

    Citation: Infectious Diseases of Poverty 2020 9:116

    Content type: Research Article

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  19. Caledonian Stadium, the main mass temporary shelter for homeless people in the City of Tshwane, was created as a local response to the imperatives of the novel coronavirus disease (COVID-19) National State of ...

    Authors: Tessa S. Marcus, Jan Heese, Andrew Scheibe, Shaun Shelly, Sasha X. Lalla and Jannie F. Hugo

    Citation: Harm Reduction Journal 2020 17:60

    Content type: Research

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  20. The coronavirus disease 2019 (COVID-19) pandemic may raise unique challenges for individuals with experience of eating disorders. Many factors have potential for detrimental impacts on psychological wellbeing ...

    Authors: Dawn Branley-Bell and Catherine V. Talbot

    Citation: Journal of Eating Disorders 2020 8:44

    Content type: Research article

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  21. The emerging infectious disease, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a serious threat in China and worldwide. Challenged by this se...

    Authors: Tie-Long Xu, Mei-Ying Ao, Xu Zhou, Wei-Feng Zhu, He-Yun Nie, Jian-He Fang, Xin Sun, Bin Zheng and Xiao-Fan Chen

    Citation: Infectious Diseases of Poverty 2020 9:115

    Content type: Short Report

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  22. The 2019 novel coronavirus disease (COVID-19) has been found in more than 200 countries worldwide since December, 2019. In China, a major reason for the rapid transmission of the COVID-19 in early stage of the...

    Authors: Zi-Han Liu, Yan-Jie Zhao, Yuan Feng, Qinge Zhang, Bao-Liang Zhong, Teris Cheung, Brian J. Hall and Yu-Tao Xiang

    Citation: Globalization and Health 2020 16:75

    Content type: Commentary

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  23. In less than 20 years, three deadly coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2, have emerged in human population causing hundreds to hundreds of thousands of deaths. Other coronaviruses are causing epizo...

    Authors: Laure Perrin-Cocon, Olivier Diaz, Clémence Jacquemin, Valentine Barthel, Eva Ogire, Christophe Ramière, Patrice André, Vincent Lotteau and Pierre-Olivier Vidalain

    Citation: Journal of Translational Medicine 2020 18:319

    Content type: Review

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  24. COVID 19-related quarantine led to a sudden and radical lifestyle changes, in particular in eating habits. Objectives of the study were to investigate the effect of quarantine on sleep quality (SQ) and body mass ...

    Authors: Luigi Barrea, Gabriella Pugliese, Lydia Framondi, Rossana Di Matteo, Daniela Laudisio, Silvia Savastano, Annamaria Colao and Giovanna Muscogiuri

    Citation: Journal of Translational Medicine 2020 18:318

    Content type: Research

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  25. The COVID-19 pandemic has exerted considerable impact on public mental health globally. With the pandemic rapidly rising in sub-Saharan Africa including Kenya, there is need to provide evidence to guide the me...

    Authors: Florence Jaguga and Edith Kwobah

    Citation: International Journal of Mental Health Systems 2020 14:68

    Content type: Review

    Published on:

  26. Healthcare resources have been strained to previously unforeseeable limits as a result of the COVID-19 pandemic of 2020. This has prompted the emergence of critical just-in-time COVID-19 education, including r...

    Authors: Mirette Dubé, Alyshah Kaba, Theresa Cronin, Sue Barnes, Tara Fuselli and Vincent Grant

    Citation: Advances in Simulation 2020 5:22

    Content type: Innovation

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  27. Azithromycin is an orally active synthetic macrolide antibiotic with a wide range of anti-bacterial, anti-inflammatory and antiviral properties. It is a safe, inexpensive, generic licenced drug available world...

    Authors: Timothy S. C. Hinks, Vicki S. Barber, Joanna Black, Susan J. Dutton, Maisha Jabeen, James Melhorn, Najib M Rahman, Duncan Richards, Daniel Lasserson, Ian D. Pavord and Mona Bafadhel

    Citation: Trials 2020 21:718

    Content type: Study protocol

    Published on:

  28. There are no specific generally accepted therapies for the coronavirus disease 2019 (COVID-19). The full spectrum of COVID-19 ranges from asymptomatic disease to mild respiratory tract illness to severe pneumo...

    Authors: Jesús Villar, José M. Añón, Carlos Ferrando, Gerardo Aguilar, Tomás Muñoz, José Ferreres, Alfonso Ambrós, César Aldecoa, Fernando Suárez-Sipmann, Kevin E. Thorpe, Peter Jüni and Arthur S. Slutsky

    Citation: Trials 2020 21:717

    Content type: Study protocol

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  29. In the rapidly evolving coronavirus disease 2019 (COVID-19) outbreak, inherent literature has been increasing at an impressive rate. Such a dynamic scenario imposes the necessity to define a new framework for ...

    Authors: Maddalena Barba, Eriseld Krasniqi, Gennaro Ciliberto and Patrizia Vici

    Citation: Journal of Translational Medicine 2020 18:315

    Content type: Commentary

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  30. As of 13 July 2020, 12.9 million COVID-19 cases have been reported worldwide. Prior studies have demonstrated that local socioeconomic and built environment characteristics may significantly contribute to vira...

    Authors: Christopher Scarpone, Sebastian T. Brinkmann, Tim Große, Daniel Sonnenwald, Martin Fuchs and Blake Byron Walker

    Citation: International Journal of Health Geographics 2020 19:32

    Content type: Research

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  31. Available studies are lacking in analysis of baseline demographics and hospital presentation of patients at risk of expiring due to coronavirus disease 2019 (COVID-19), particularly Black American patients. We...

    Authors: James Andrew McCracken, Mohamed Nakeshbandi, Jeffrey Arace, Wayne J. Riley and Roopali Sharma

    Citation: Translational Medicine Communications 2020 5:12

    Content type: Research

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  32. Medical care workers experienced unprecedented levels of workload and pressure since the outbreak of coronavirus disease 2019 (COVID-19). Little is known about its exact impact on medical care workers and rela...

    Authors: Ming-Yu Si, Xiao-You Su, Yu Jiang, Wen-Jun Wang, Xiao-Fen Gu, Li Ma, Jing Li, Shao-Kai Zhang, Ze-Fang Ren, Ran Ren, Yuan-Li Liu and You-Lin Qiao

    Citation: Infectious Diseases of Poverty 2020 9:113

    Content type: Research Article

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  33. The outbreak of coronavirus disease 2019 (COVID-19) had spread worldwide. Although the world has intensively focused on the epidemic center during this period of time, it is imperative to emphasize that more a...

    Authors: Ru-Jun Liao, Chun-Nong Ji-Ke, Tao Zhang, Qiang Liao, Ling Li, Tian-Yu Zhu and Shao-Yong Bian

    Citation: Infectious Diseases of Poverty 2020 9:112

    Content type: Case Study

    Published on:

  34. Psychological distress is highly prevalent among migraineurs during public health emergencies. The coronavirus disease 2019 (nCOV-2019) has created mass panic in China due to its highly contagious by contact a...

    Authors: Mengmeng Ma, Jinghuan Fang, Changling Li, Jiajia Bao, Yang Zhang, Ning Chen, Jian Guo and Li He

    Citation: The Journal of Headache and Pain 2020 21:100

    Content type: Research article

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  35. The German government has made it mandatory to wear respiratory masks covering mouth and nose (MNC) as an effective strategy to fight SARS-CoV-2 infections. In many countries, this directive has been extended ...

    Authors: Christiane Matuschek, Friedrich Moll, Heiner Fangerau, Johannes C. Fischer, Kurt Zänker, Martijn van Griensven, Marion Schneider, Detlef Kindgen-Milles, Wolfram Trudo Knoefel, Artur Lichtenberg, Balint Tamaskovics, Freddy Joel Djiepmo-Njanang, Wilfried Budach, Stefanie Corradini, Dieter Häussinger, Torsten Feldt…

    Citation: European Journal of Medical Research 2020 25:32

    Content type: Review

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  36. Measures aiming at containing the Coronavirus disease 2019 (COVID-19) include isolation, social distancing, and quarantine. Quarantine and other lockdown instruments show promise in reducing the number of COVI...

    Authors: Eszter Füzéki, David A. Groneberg and Winfried Banzer

    Citation: Journal of Occupational Medicine and Toxicology 2020 15:25

    Content type: Review

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  37. The coronavirus disease 2019 (COVID-19) epidemic met coincidentally with massive migration before Lunar New Year in China in early 2020. This study is to investigate the relationship between the massive migrat...

    Authors: Wen-Yu Song, Pan Zang, Zhong-Xing Ding, Xin-Yu Fang, Li-Guo Zhu, Ya Zhu, Chang-Jun Bao, Feng Chen, Ming Wu and Zhi-Hang Peng

    Citation: Infectious Diseases of Poverty 2020 9:109

    Content type: Research Article

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  38. As the outbreak of coronavirus disease 2019 (COVID-19) has progressed, computed tomography has emerged as an integral part of the diagnosis alongside reverse transcriptase–polymerase chain reaction assays. Fre...

    Authors: Mohsin Sheraz Mughal, Rameez Rehman, Ramy Osman, Nathan Kan, Hasan Mirza and Margaret H. Eng

    Citation: Journal of Medical Case Reports 2020 14:124

    Content type: Case report

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  39. Healthcare workers (HCWs) are at particular risk during pandemics and epidemics of highly virulent diseases with significant morbidity and case fatality rate. These diseases include severe acute respiratory sy...

    Authors: Ana Licina, Andrew Silvers and Rhonda L. Stuart

    Citation: Systematic Reviews 2020 9:173

    Content type: Systematic review update

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  40. The first reports of the Chinese experience in the management of newborns of mothers with SARS-CoV 2 infection did not recommend mother-baby contact or breastfeeding. At present, the most important Internation...

    Authors: Augusto Pereira, Sara Cruz-Melguizo, Maria Adrien, Lucia Fuentes, Eugenia Marin, Azul Forti and Tirso Perez-Medina

    Citation: International Breastfeeding Journal 2020 15:69

    Content type: Research

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  41. COVID-19 pandemia is affecting Countries worldwide with a gendered death excess as being a male represents, especially in the 50–69 years age group, an unfavourable factor. Females are constitutionally prone t...

    Authors: Lorenzo Salvati, Benedetta Biagioni, Emanuele Vivarelli and Paola Parronchi

    Citation: Clinical and Molecular Allergy 2020 18:14

    Content type: Review

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  42. The severe acute respiratory syndrome virus SARS-CoV-2, a close relative of the SARS-CoV virus, is the cause of the recent COVID-19 pandemic affecting, to date, over 14 million individuals across the globe and...

    Authors: Nophar Geifman and Anthony D. Whetton

    Citation: Journal of Translational Medicine 2020 18:297

    Content type: Research

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  43. The World Health Organization declared on March 11, 2020, that the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) has escalated from epidemic into pandemic. As the initial outbreak ...

    Authors: Yuxi Li, Juan Li, Dongling Zhong, Yue Zhang, Yonggang Zhang, Yan Guo, Mike Clarke and Rongjiang Jin

    Citation: Systematic Reviews 2020 9:170

    Content type: Protocol

    Published on:

  44. More severe cases of COVID- 19 are more likely to be hospitalized and around one-fifth, needing ICU admission. Understanding the common laboratory features of COVID-19 in more severe cases versus non-severe pa...

    Authors: Sulmaz Ghahramani, Reza Tabrizi, Kamran B. Lankarani, Seyyed Mohammad Amin Kashani, Shahla Rezaei, Nazanin Zeidi, Maryam Akbari, Seyed Taghi Heydari, Hamed Akbari, Peyman Nowrouzi-Sohrabi and Fariba Ahmadizar

    Citation: European Journal of Medical Research 2020 25:30

    Content type: Review

    Published on: