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Coronavirus research highlights

A novel coronavirus, 2019-nCoV, has been identified as the cause of an outbreak of respiratory illness that originated in Wuhan, China, and which has spread to several other countries around the world.  Recent content from BMC and SpringerOpen journals relevant to coronavirus research, as well as additional commentary on this topic, is included below. 

BMC, as part of Springer Nature, encourages early sharing of research submitted to all our journals through preprints, and our In Review preprint service is available for many journals. We strongly urge authors submitting articles related to this emergency to BMC journals to share underlying interim and final research datasets relating to the outbreak as rapidly and widely as possible, including with public health and research communities and the WHO.

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  1. Acute respiratory distress syndrome virus-2 (SARS-CoV-2) responsible for coronavirus disease 2019 (COVID-19) infection, which causes global public health emergencies, has sped widely for more than 5 months and...

    Authors: Hongbing Peng, Tiefeng Gong, Xiaoying Huang, Xun Sun, Hong Luo, Weizhong Wang, Junbiao Luo, Baowei Luo, Yanhui Chen, Xingxing Wang, Haifeng Long, Hua Mei, Chuang Li, Yanni Dai and Honghui Li

    Citation: Stem Cell Research & Therapy 2020 11:291

    Content type: Short report

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  2. Since the first case of coronavirus disease 2019 (COVID-19) in Africa was detected on February 14, 2020, the cumulative confirmations reached 15 207 including 831 deaths by April 13, 2020. Africa has been desc...

    Authors: Salihu S. Musa, Shi Zhao, Maggie H. Wang, Abdurrazaq G. Habib, Umar T. Mustapha and Daihai He

    Citation: Infectious Diseases of Poverty 2020 9:96

    Content type: Research Article

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  3. Coronavirus disease 2019 (COVID-19) has caused a serious epidemic around the world, but it has been effectively controlled in the mainland of China. The Chinese government limited the migration of people almos...

    Authors: Yong Li, Lian-Wen Wang, Zhi-Hang Peng and Hong-Bing Shen

    Citation: Infectious Diseases of Poverty 2020 9:94

    Content type: Research Article

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  4. The world is facing a massive burden from the coronavirus disease 2019 (COVID-19) pandemic. Governments took the extraordinary step of locking down their own countries to curb the spread of the coronavirus. Af...

    Authors: Pier Luigi Ingrassia, Giorgio Capogna, Cristina Diaz-Navarro, Demian Szyld, Stefania Tomola and Esther Leon-Castelao

    Citation: Advances in Simulation 2020 5:13

    Content type: Debate article

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  5. Severe acute respiratory syndrome (SARS)-CoV-2-induced coronavirus disease-2019 (COVID-19) is a pandemic disease that affects > 2.8 million people worldwide, with numbers increasing dramatically daily. However...

    Authors: Jincheng Xu, Xiaoyue Xu, Lina Jiang, Kamal Dua, Philip M. Hansbro and Gang Liu

    Citation: Respiratory Research 2020 21:182

    Content type: Research

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  6. In December 2019, the outbreak of a disease subsequently termed COVID-19 occurred in Wuhan, China. The number of cases increased rapidly and spread to six continents. However, there is limited information on t...

    Authors: Jie Zhang, Guangping Meng, Wei Li, Bingqing Shi, Hongna Dong, Zhenzhong Su, Qian Huang and Peng Gao

    Citation: Respiratory Research 2020 21:180

    Content type: Research

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  7. The COVID-19 pandemic, caused by SARS-CoV-2 virus, has resulted in over 100,000 deaths in the USA. Our institution has treated over 2000 COVID-19 patients during the pandemic in New York City. The pandemic dir...

    Authors: Bo Wang, Oliver Van Oekelen, Tarek H. Mouhieddine, Diane Marie Del Valle, Joshua Richter, Hearn Jay Cho, Shambavi Richard, Ajai Chari, Sacha Gnjatic, Miriam Merad, Sundar Jagannath, Samir Parekh and Deepu Madduri

    Citation: Journal of Hematology & Oncology 2020 13:94

    Content type: Research

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  8. The COVID-19 pandemic is a complex global public health crisis presenting clinical, organisational and system-wide challenges. Different research perspectives on health are needed in order to manage and monito...

    Authors: D. Kringos, F. Carinci, E. Barbazza, V. Bos, K. Gilmore, O. Groene, L. Gulácsi, D. Ivankovic, T. Jansen, S. P. Johnsen, S. de Lusignan, J. Mainz, S. Nuti and N. Klazinga

    Citation: Health Research Policy and Systems 2020 18:80

    Content type: Commentary

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  9. Bacillus Calmette-Guérin (BCG) vaccination is routine and near-universal in many low- and middle-income countries (LMIC). It has been suggested that BCG can have a protective effect on COVID-19 morbidity and m...

    Authors: Marcos Pereira, Enny Paixão, Anete Trajman, Ramon Andrade de Souza, Marcio Santos da Natividade, Julia M. Pescarini, Susan Martins Pereira, Florisneide Rodrigues Barreto, Ricardo Ximenes, Margareth Dalcomo, Maria Yury Ichihara, Ceuci Nunes, Manoel Barral-Netto and Maurício L. Barreto

    Citation: Respiratory Research 2020 21:178

    Content type: Letter to the Editor

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  10. The recent outbreak by SARS-CoV-2 has generated a chaos in global health and economy and claimed/infected a large number of lives. Closely resembling with SARS CoV, the present strain has manifested exceptiona...

    Authors: Amrita Banerjee, Dipannita Santra and Smarajit Maiti

    Citation: Journal of Translational Medicine 2020 18:281

    Content type: Research

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  11. Shenzhen is a city of 22 million people in south China that serves as a financial and trade center for East Asia. The city has extensive ties to Hubei Province, the first reported epicenter of the coronavirus ...

    Authors: Huachun Zou, Yuelong Shu and Tiejian Feng

    Citation: Infectious Diseases of Poverty 2020 9:89

    Content type: Commentary

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  12. The new coronavirus disease COVID-19 began in December 2019 and has spread rapidly by human-to-human transmission. This study evaluated the transmissibility of the infectious disease and analyzed its associati...

    Authors: Xiao-Jing Guo, Hui Zhang and Yi-Ping Zeng

    Citation: Infectious Diseases of Poverty 2020 9:87

    Content type: Research Article

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  13. The positive predictive effect of altruism on physical and psychological well-being has been extensively demonstrated in previous studies, but few studies have examined the effect of altruism on negative menta...

    Authors: Yi Feng, Min Zong, Zhizun Yang, Wen Gu, Dan Dong and Zhihong Qiao

    Citation: Globalization and Health 2020 16:61

    Content type: Research

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  14. Severe acute respiratory syndrome (SARS) has been initiating pandemics since the beginning of the century. In December 2019, the world was hit again by a devastating SARS episode that has so far infected almos...

    Authors: Nitin Chitranshi, Vivek K. Gupta, Rashi Rajput, Angela Godinez, Kanishka Pushpitha, Ting Shen, Mehdi Mirzaei, Yuyi You, Devaraj Basavarajappa, Veer Gupta and Stuart L. Graham

    Citation: Journal of Translational Medicine 2020 18:278

    Content type: Research

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  15. Coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) recently was declared a pandemic by world health organization (WHO) Due to sudden outbreaks, currently, no ...

    Authors: Shahid Hussain, Ya-Jia Xie, Dan Li, Shaukat Iqbal Malik, Jin-cai Hou, Elaine Lai-Han Leung and Xing-Xing Fan

    Citation: Chinese Medicine 2020 15:70

    Content type: Review

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  16. Coronavirus Disease is impacting the entire world. As the first country that has needed to confront this disease, China has responded with unprecedented and hugely successful public health initiatives. Almost ...

    Authors: Shitao Chen, Feihan Li, Chaihua Lin, Yuge Han, Xilun Nie, Robert N. Portnoy and Zhihong Qiao

    Citation: Globalization and Health 2020 16:59

    Content type: Commentary

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  17. Novel coronavirus SARS-CoV-2 is known to be susceptible in vitro to exposure to hydroxychloroquine and its effect has been found to be potentiated by azithromycin. We hypothesise that early administration of h...

    Authors: František Duška, Petr Waldauf, Milada Halačová, Václav Zvoníček, Jakub Bala, Martin Balík, Jan Beneš, Olga Klementová, Irena Kozáková, Viktor Kubricht, Anne Le Roy, Tomáš Vymazal, Veronika Řehořová and Vladimír Černý

    Citation: Trials 2020 21:631

    Content type: Study protocol

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  18. The outbreak of COVID-19 (caused by SARS-Cov-2) is very serious, and no effective antiviral treatment has yet been confirmed. The adage “old drug, new trick” in this context may suggest the important therapeut...

    Authors: Xi Liu, Huili Chen, Yuqi Shang, Hongqiong Zhu, Gongqi Chen, Yuanli Chen, Shaoxuan Liu, Yaoyong Zhou, Mingxing Huang, Zhongsi Hong and Jinyu Xia

    Citation: Trials 2020 21:622

    Content type: Study protocol

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  19. The Coronavirus disease (COVID-19) is highly infectious, with the recent World Health Organization decree confirming a global public health emergency. The outcomes related to maternal and fetal health among pr...

    Authors: Juliana Vasconcellos Freitas-Jesus, Larissa Rodrigues and Fernanda Garanhani Surita

    Citation: Reproductive Health 2020 17:108

    Content type: Study protocol

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  20. The outbreak of coronavirus disease 2019 (COVID-19) is now becoming an enormous threat to public health. The clinical spectrum of COVID-19 is extensive, of which critical cases are with rapid disease progressi...

    Authors: Shan-Yan Zhang, Jiang-Shan Lian, Jian-Hua Hu, Xiao-Li Zhang, Ying-Feng Lu, Huan Cai, Jue-Qing Gu, Chan-Yuan Ye, Ci-Liang Jin, Guo-Dong Yu, Hong-Yu Jia, Yi-Min Zhang, Ji-Fang Sheng, Lan-Juan Li and Yi-Da Yang

    Citation: Infectious Diseases of Poverty 2020 9:85

    Content type: Research Article

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  21. Since January 2020, after Chinese health authorities identified a new type of coronavirus (SARS-CoV-2), the virus has spread throughout China and consecutively throughout the whole world. The most common sympt...

    Authors: Anne Lampe, Alexander Winschel, Cornelie Lang and Thorsten Steiner

    Citation: Neurological Research and Practice 2020 2:19

    Content type: Letter to the editor

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  22. Since the outbreak of coronavirus disease 2019 (COVID-19), many researchers in China have performed related clinical research. However, systematic reviews of the registered clinical trials are still lacking. T...

    Authors: Rui-fang Zhu, Yu-lu Gao, Sue-Ho Robert, Jin-ping Gao, Shi-gui Yang and Chang-tai Zhu

    Citation: Journal of Translational Medicine 2020 18:274

    Content type: Review

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  23. Previous studies have shown that Coronavirus Disease 2019 (COVID-19) patients with underlying comorbidities can have worse outcomes. However, the effect of hypertension on outcomes of COVID-19 patients remains...

    Authors: Qing Yang, Ying Zhou, Xinrong Wang, Shan Gao, Yang Xiao, Weiming Zhang, Yi Hu and Yafei Wang

    Citation: Respiratory Research 2020 21:172

    Content type: Research

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  24. There was much evidence suggesting that the serum lactate dehydrogenase (LDH) levels reflect the extent of various pathophysiological processes. However, the current information about dynamic change of LDH in ...

    Authors: Mei-ying Wu, Lin Yao, Yi Wang, Xin-yun Zhu, Xia-fang Wang, Pei-jun Tang and Cheng Chen

    Citation: Respiratory Research 2020 21:171

    Content type: Research

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  25. Preliminary reports suggest that the Coronavirus Disease 2019 (COVID− 19) pandemic has led to disproportionate morbidity and mortality among historically disadvantaged populations. We investigate the racial an...

    Authors: Aniruddh P. Patel, Manish D. Paranjpe, Nina P. Kathiresan, Manuel A. Rivas and Amit V. Khera

    Citation: International Journal for Equity in Health 2020 19:114

    Content type: Letter to the Editor

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  26. Healthy childhood development is fostered through sufficient physical activity (PA; including time outdoors), limiting sedentary behaviours (SB), and adequate sleep; collectively known as movement behaviours. ...

    Authors: Sarah A. Moore, Guy Faulkner, Ryan E. Rhodes, Mariana Brussoni, Tala Chulak-Bozzer, Leah J. Ferguson, Raktim Mitra, Norm O’Reilly, John C. Spence, Leigh M. Vanderloo and Mark S. Tremblay

    Citation: International Journal of Behavioral Nutrition and Physical Activity 2020 17:85

    Content type: Research

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  27. The coronavirus disease 2019 (COVID-19) outbreak has seriously endangered the health and lives of Chinese people. In this study, we predicted the COVID-19 epidemic trend and estimated the efficacy of several i...

    Authors: Jian Zu, Miao-Lei Li, Zong-Fang Li, Ming-Wang Shen, Yan-Ni Xiao and Fan-Pu Ji

    Citation: Infectious Diseases of Poverty 2020 9:83

    Content type: Research Article

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  28. The COVID-19 pandemic has had a significant impact on public mental health. Therefore, monitoring and oversight of the population mental health during crises such as a panedmic is an immediate priority. The ai...

    Authors: Nader Salari, Amin Hosseinian-Far, Rostam Jalali, Aliakbar Vaisi-Raygani, Shna Rasoulpoor, Masoud Mohammadi, Shabnam Rasoulpoor and Behnam Khaledi-Paveh

    Citation: Globalization and Health 2020 16:57

    Content type: Research

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  29. The rapid spread of the SARS-CoV-2 epidemic has simultaneous time and space dynamics. This behaviour results from a complex combination of factors, including social ones, which lead to significant differences ...

    Authors: Leonardo Azevedo, Maria João Pereira, Manuel C. Ribeiro and Amílcar Soares

    Citation: International Journal of Health Geographics 2020 19:25

    Content type: Methodology

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  30. The novel coronavirus disease 2019 (COVID-19) broke out globally. Early prediction of the clinical progression was essential but still unclear. We aimed to evaluate the timeline of COVID-19 development and ana...

    Authors: Fang Wang, Mengyuan Qu, Xuan Zhou, Kai Zhao, Changxiang Lai, Qiyuan Tang, Wenjie Xian, Ruikun Chen, Xuan Li, Zhiyu Li, Qing He and Lei Liu

    Citation: Journal of Translational Medicine 2020 18:270

    Content type: Research

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  31. Since December 2019, the outbreak of COVID-19 caused a large number of hospital admissions in China. Many patients with COVID-19 have symptoms of acute respiratory distress syndrome, even are in danger of deat...

    Authors: Wenjing Ye, Guoxi Chen, Xiaopan Li, Xing Lan, Chen Ji, Min Hou, Di Zhang, Guangwang Zeng, Yaling Wang, Cheng Xu, Weiwei Lu, Ruolin Cui, Yuyang Cai, Hai Huang and Ling Yang

    Citation: Respiratory Research 2020 21:169

    Content type: Research

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  32. The primary objectives of the study are:

    Authors: Raquel González, Laura García-Otero, Clara Pons-Duran, Elena Marbán-Castro, Anna Goncé, Elisa Llurba, Maria del Mar Gil, Miguel Ángel Rodríguez-Zambrano, Haily Chen, Máximo Ramírez, Azucena Bardají and Clara Menendez

    Citation: Trials 2020 21:607

    Content type: Letter

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  33. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to the outbreak of pneumonia in Wuhan. The virus is highly infectious. Patients with cancer might be susceptible to the viral infection beca...

    Authors: Shi-Hui Song, Tie-Long Chen, Li-Ping Deng, Yong-Xi Zhang, Ping-Zheng Mo, Shi-Cheng Gao, Wen-Jia Hu, Yong Xiong and Zhi-Yong Ma

    Citation: Infectious Diseases of Poverty 2020 9:82

    Content type: Case Report

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  34. This editorial describes why surge planning in the community must account for potential infection outbreaks in jails and prisons, and why incarcerated people and those in contact with them, including over 450,...

    Authors: Oluwadamilola T. Oladeru, Nguyen-Toan Tran, Tala Al-Rousan, Brie Williams and Nickolas Zaller

    Citation: Health & Justice 2020 8:17

    Content type: Letter to the Editor

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  35. There is currently considerable international debate around school closures/openings and the role of children in the transmission of coronavirus disease 2019 (COVID-19). Whilst evidence suggests that children ...

    Authors: Darren J. Gray, Johanna Kurscheid, Mary Lorraine Mationg, Gail M. Williams, Catherine Gordon, Matthew Kelly, Kinley Wangdi and Donald P. McManus

    Citation: Infectious Diseases of Poverty 2020 9:81

    Content type: Opinion

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  36. COVID-19, the novel coronavirus affecting the most part of worldwide countries since early 2020, is fast increasing its prevalence around the world, representing a significant emergency for the population and ...

    Authors: Sebastiano Gangemi, Lucia Billeci and Alessandro Tonacci

    Citation: Clinical and Molecular Allergy 2020 18:12

    Content type: Correspondence

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  37. In December 2019, 27 cases of pneumonia, of unknown cause, were identified in the province of Hubei (China). The WHO declared the situation as a Public Health Emergency of International Concern, and it was fin...

    Authors: Juan Jose Gonzalez-Gerez, Carlos Bernal-Utrera, Ernesto Anarte-Lazo, Jose Antonio Garcia-Vidal, Jose Martin Botella-Rico and Cleofas Rodriguez-Blanco

    Citation: Trials 2020 21:588

    Content type: Study protocol

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  38. Amino-bisphosphonates such as zoledronic acid (ZA) can possibly ameliorate or prevent severe COVID-19 disease by at least three distinct mechanisms: (1) as immunostimulants which could boost γδ T cell expansio...

    Authors: Adam Brufsky, Juan Luis Gomez Marti, Azadeh Nasrazadani and Michael T. Lotze

    Citation: Journal of Translational Medicine 2020 18:261

    Content type: Review

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  39. This study investigated the influence of Coronavirus Disease 2019 (COVID-19) on lung function in early convalescence phase.

    Authors: Yiying Huang, Cuiyan Tan, Jian Wu, Meizhu Chen, Zhenguo Wang, Liyun Luo, Xiaorong Zhou, Xinran Liu, Xiaoling Huang, Shican Yuan, Chaolin Chen, Fen Gao, Jin Huang, Hong Shan and Jing Liu

    Citation: Respiratory Research 2020 21:163

    Content type: Research

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  40. It is well established that obesity is a disease of sustained low-grade inflammation. However, it is currently unknown if obesity plays a role in the clinical manifestations and prognosis of severe acute respi...

    Authors: Shao-Hang Cai, Wei Liao, Shu-Wei Chen, Li-Li Liu, Si-Yao Liu and Zhi-Dan Zheng

    Citation: Infectious Diseases of Poverty 2020 9:80

    Content type: Research Article

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  41. Coronavirus disease 2019 (COVID-19) is now a global public threat. Given the pandemic of COVID-19, the economic impact of COVID-19 is essential to add value to the policy-making process. We retrospectively con...

    Authors: Xue-Zheng Li, Feng Jin, Jian-Guo Zhang, Yun-Feng Deng, Wei Shu, Jing-Min Qin, Xin Ma and Yu Pang

    Citation: Infectious Diseases of Poverty 2020 9:78

    Content type: Research Article

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  42. In this study, we investigate the effect of hydroxychloroquine on the prevention of Novel Coronavirus Disease (COVID-19) in cancer patients being treated.

    Authors: Abolghasem Allahyari, Hossein Rahimi, Majid Khadem-Rezaiyan, Zahra Mozaheb, Mohsen Seddigh-Shamsi, Alireza Bary, Mostafa Kamandi, Sajad Ataei Azimi, Saeed Eslami HasanAbadi, Alireza Noferesti, Somayeh Sadat Shariatmaghani, Houshang Rafatpanah, Shohreh Khatami, Afshin Jabbar Imani, Hassan Mortazi and Mohammad Moeini Nodeh

    Citation: Trials 2020 21:575

    Content type: Letter

    Published on:

  43. The COVID-19 is disproportionally affecting the poor, minorities and a broad range of vulnerable populations, due to its inequitable spread in areas of dense population and limited mitigation capacity due to h...

    Authors: Efrat Shadmi, Yingyao Chen, Inês Dourado, Inbal Faran-Perach, John Furler, Peter Hangoma, Piya Hanvoravongchai, Claudia Obando, Varduhi Petrosyan, Krishna D. Rao, Ana Lorena Ruano, Leiyu Shi, Luis Eugenio de Souza, Sivan Spitzer-Shohat, Elizabeth Sturgiss, Rapeepong Suphanchaimat…

    Citation: International Journal for Equity in Health 2020 19:104

    Content type: Commentary

    Published on:

  44. The recent global pandemic has placed a high priority on identifying drugs to prevent or lessen clinical infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), caused by Coronavirus disease...

    Authors: Jason Kim, Jenny Zhang, Yoonjeong Cha, Sarah Kolitz, Jason Funt, Renan Escalante Chong, Scott Barrett, Rebecca Kusko, Ben Zeskind and Howard Kaufman

    Citation: Journal of Translational Medicine 2020 18:257

    Content type: Research

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  45. Currently, coronavirus disease 2019 (COVID-19) is continuously and rapidly circulating, causing heavy damage on public health. No effective antiviral treatment has been proved thus far. Traditional Chinese med...

    Authors: Bangjiang Fang, Wen Zhang, Xinxin Wu, Tingrong Huang, Huacheng Li, You Zheng, Jinhua Che, Shuting Sun, Chao Jiang, Shuang Zhou and Jun Feng

    Citation: Trials 2020 21:568

    Content type: Study protocol

    Published on:

  46. During the COVID-19 pandemic, as a large city located in Southwest China, Chengdu was mainly affected by imported cases. For a psychiatric hospital, the enclosed management model, the crowded wards and the unc...

    Authors: Jiajia Chen, Maoxiang Xiong, Zongling He, Wen Shi, Yuchuan Yue and Manxi He

    Citation: Globalization and Health 2020 16:53

    Content type: Letter to the Editor

    Published on: