Guest Editor:
Dr Andras Bikov, MD, PhD, Wythenshawe Hospital, Manchester University NHS Foundation Trust, United Kingdom
Lipids in Health and Disease is calling for submissions to our new Collection on "Lipids and Sleep". This Collection is focusing on the link between sleep and lipid metabolism. We invite original research, topical and systematic review articles and meta-analyses.
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Sleep disorders affect billions of people worldwide and are known to contribute to cardiovascular disorders. Dyslipidemia is a hallmark of cardiovascular disease; therefore, understanding the link between normal and abnormal sleep as well as lipid metabolism has important clinical implications.
Despite extensive research in this field, the exact link between abnormal sleep and dyslipidemia is not fully known. It seems that the relationship is not linear and is affected by genetics, epigenetics, demographics, socioeconomic, physiological and pathological factors. We should not forget that the physiological production of hormones and enzymes regulating appetite and lipid metabolism show sleep-related or circadian dependency. However, sleep need and chronotype have interindividual variations. Sleep disorders that are associated with hypoxaemia, inflammation or sympathetic system activation further contribute to these changes.
The Collection focuses on the link between sleep and lipid metabolism. We invite original research, topical and systematic review articles and meta-analyses. Manuscripts on pediatric and adult human studies and experimental animal and cell culture models will equally be accepted. Most importantly, we encourage submissions of clinical trials focusing on sleep and lipids.
The Collection will cover the following:
• The physiological link between normal sleep, diet and lipid metabolism.
• The effect of diet and anti-lipid medications on sleep.
• The association between insomnia and lipid metabolism. How would cognitive behavioral therapy or pharmacological treatment affect lipid values?
• The association between circadian rhythm disorders and lipid metabolism. Can chronotherapy, light therapy or diet personalized on the person’s chronotype modify lipid values?
• The association between sleep-related breathing disorders and lipid metabolism. What is the effect of positive airway pressure, oral appliances and surgery on lipid levels?
• The association between parasomnia and lipid metabolism. Is there a link? How would therapy affect lipid concentrations?
• The association between sleep-related movement disorders and lipid metabolism. Are all sleep-related movement diseases detrimental to lipid values? What is the effect of pharmacological treatments of sleep-related movement diseases?
• The association between hypersomnolence of central origin and lipid metabolism. Would narcolepsy treatment improve lipid levels?
Obesity refers to a significant contributor to the development of obstructive sleep apnea (OSA). Early prediction of OSA usually leads to better treatment outcomes, and this study aims to employ novel metaboli...
Obstructive sleep apnea (OSA) has a bidirectional association with metabolic syndrome, and insulin resistance (IR). The triglyceride-glucose (TyG) index could be a simply calculated marker of IR in OSA. Howeve...
The ZJU index, a novel calculation that combines body mass index, triglycerides, fasting blood glucose and the ratio of alanine aminotransferase to aspartate aminotransferase, is a closely related measure of o...
Currently, there is limited and controversial clinical research on the correlation between sleep-disordered breathing (SDB) and dyslipidemia. This discrepancy in findings may be because studies that primarily ...
Before submitting your manuscript, please ensure you have read our submission guidelines. Articles for this Collection should be submitted via our submission system, Snapp. During the submission process you will be asked whether you are submitting to a Collection, please select "Lipids and Sleep" from the dropdown menu.
Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.
The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editorial Board Member who has no competing interests.