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How to treat severe infections in the ICU

  1. Fungal infections represent a major burden in the critical care setting with increasing morbidity and mortality. Candidiasis is the leading cause of such infections, with C. albicans being the most common causati...

    Authors: Dimitrios K Matthaiou, Theodora Christodoulopoulou and George Dimopoulos
    Citation: BMC Infectious Diseases 2015 15:205
  2. Bloodstream infections (BSIs) are frequent in ICU and is a prognostic factor of severe sepsis. Community acquired BSIs usually due to susceptible bacteria should be clearly differentiated from healthcare assoc...

    Authors: Jean-François Timsit, Jean-François Soubirou, Guillaume Voiriot, Sarah Chemam, Mathilde Neuville, Bruno Mourvillier, Romain Sonneville, Eric Mariotte, Lila Bouadma and Michel Wolff
    Citation: BMC Infectious Diseases 2014 14:489
  3. Patients with severe viral infections are often hospitalized in intensive care units (ICUs) and recent studies underline the frequency of viral detection in ICU patients. Viral infections in the ICU often invo...

    Authors: Theodoros Kelesidis, Ioannis Mastoris, Aliki Metsini and Sotirios Tsiodras
    Citation: BMC Infectious Diseases 2014 14:321
  4. High mortality and morbidity rates associated with severe infections in the critically ill continue to be a significant issue for the healthcare system. In view of the diverse and unique pharmacokinetic profil...

    Authors: Gloria Wong, Fekade Bruck Sime, Jeffrey Lipman and Jason A Roberts
    Citation: BMC Infectious Diseases 2014 14:288
  5. The management of infections in surgical intensive care unit patients poses specific challenges. Although the overall approach to the patient is no different from other patients, diagnosis is often problematic...

    Authors: Jan De Waele and Liesbet De Bus
    Citation: BMC Infectious Diseases 2014 14:193
  6. The increasing occurrence of multidrug resistant (MDR) bacteria arises at a time when there is a lack of antibiotics active against these pathogens and few new antimicrobials are in the pipelines of the pharma...

    Authors: José Garnacho-Montero, Yael Corcia-Palomo, Rosario Amaya-Villar and Luis Martin-Villen
    Citation: BMC Infectious Diseases 2014 14:135
  7. Microaspiration of subglottic secretions through channels formed by folds in high volume-low pressure poly-vinyl chloride cuffs of endotracheal tubes is considered a significant pathogenic mechanism of ventila...

    Authors: Stijn I Blot, Jan Poelaert and Marin Kollef
    Citation: BMC Infectious Diseases 2014 14:119
  8. Gram-positive bacteria to include methicillin-resistant Staphylococcus aureus (MRSA), methicillin-susceptible Staphylococcus aureus (MSSA), and enterococci, to include vancomycin-resistant enterococci (VRE), disp...

    Authors: Cristina Vazquez-Guillamet and Marin H Kollef
    Citation: BMC Infectious Diseases 2014 14:92
  9. Ventilator-associated pneumonia (VAP) is one of the most frequent clinical problems in ICU with an elevated morbidity and costs associated with it, in addition to prolonged MV, ICU-length of stay (LOS) and hos...

    Authors: Bárbara Borgatta and Jordi Rello
    Citation: BMC Infectious Diseases 2014 14:211