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Antimicrobial Resistance

New Content Item © James Gathany/CDCEdited by Laith Yakob, London School of Hygiene and Tropical Medicine, UK

Antimicrobial resistance (AMR) causes almost 1 million deaths every year and its accelerating spread ensures an even greater burden in the years to come. At the 70th World Health Assembly held in Geneva in May 2017 the new Director-General of the WHO, Dr Tedros Adhanom, described AMR as "the perfect example of the complex, multi-sectorial, multi-stakeholder challenges we will increasingly face in the future".

This series aims to explore the many facets of AMR, be they biological, clinical, environmental, epidemiological or economic. 

  2. Antibiotics remain the cornerstone of modern medicine. Yet there exists an inherent dilemma in their use: we are able to prevent harm by administering antibiotic treatment as necessary to both humans and anima...

    Authors: Gwenan M. Knight, Nicholas G. Davies, Caroline Colijn, Francesc Coll, Tjibbe Donker, Danna R. Gifford, Rebecca E. Glover, Mark Jit, Elizabeth Klemm, Sonja Lehtinen, Jodi A. Lindsay, Marc Lipsitch, Martin J. Llewelyn, Ana L. P. Mateus, Julie V. Robotham, Mike Sharland…
    Citation: BMC Infectious Diseases 2019 19:1011
    Content type: Debate Published on:

  3. Bacterial infection of the urinary tract is among the common reasons for seeking medical attention in the community. Rapidly increasing antibiotic resistance of uropathogens is resulting in limited treatment o...

    Authors: Guesh Gebremariam, Haftom Legese, Yemane Woldu, Tadele Araya, Kiflom Hagos and Araya GebreyesusWasihun
    Citation: BMC Infectious Diseases 2019 19:950
    Content type: Research article Published on:

  4. On 7th June, 2018, a primary school in Beijing, China notified Shunyi CDC of an outbreak of acute respiratory disease characterized by fever and cough among students and resulting in nine hospitalization cases...

    Authors: Wen-Zeng Zhang, Song-Jian Zhang, Quan-Yi Wang, Yin-Dong Li, Hong-Bo Jing, Guang-Yi Hu and Dan Wu
    Citation: BMC Infectious Diseases 2019 19:871
    Content type: Research article Published on:

  5. The effectiveness of Helicobacter pylori first-line treatment has decreased drastically with the rise of strains resistant to clarithromycin. Therapy failure has also been described in patients with infections by...

    Authors: Betsy Verónica Arévalo-Jaimes, Diana F. Rojas-Rengifo, Carlos Alberto Jaramillo, Belén Mendoza de Molano, José Fernando Vera-Chamorro and María del Pilar Delgado
    Citation: BMC Infectious Diseases 2019 19:546
    Content type: Research article Published on:

  6. Typhoid fever remains a major public health problem in Zimbabwe with recurrent outbreaks reported since 2009. To provide guidance on appropriate treatment choice in order to minimise the morbidity and mortalit...

    Authors: Tapfumanei Mashe, Muchaneta Gudza-Mugabe, Andrew Tarupiwa, Ellen Munemo, Sekesai Mtapuri-Zinyowera, Shannon L. Smouse, Arvinda Sooka, Babill Stray-Pedersen, Anthony M. Smith and Joshua Mbanga
    Citation: BMC Infectious Diseases 2019 19:487
    Content type: Research article Published on:

  7. Rapid detection of rifampicin resistance is essential for early management and prevention of transmission of multidrug-resistant tuberculosis (MDR-TB). We studied the prevalence of rifampicin resistance of Mycoba...

    Authors: Balew Arega, Fiqrte Menbere and Yitagesu Getachew
    Citation: BMC Infectious Diseases 2019 19:307
    Content type: Research article Published on:

  8. Surgical site infection (SSI) is the foremost infection in the overall patient population, affecting up to 66% of operated patients and with a frequency up to nine times more than in developed countries. This ...

    Authors: Bruke B. Billoro, Mengistu H. Nunemo and Seid E. Gelan
    Citation: BMC Infectious Diseases 2019 19:298
    Content type: Research article Published on:

  9. The Lebanese Society of Infectious Diseases and Clinical Microbiology (LSIDCM) is involved in antimicrobial stewardship. In an attempt at guiding clinicians across Lebanon in regards to the proper use of antim...

    Authors: Nicholas Haddad, Souha S. Kanj, Lyn S. Awad, Dania I. Abdallah and Rima A. Moghnieh
    Citation: BMC Infectious Diseases 2019 19:293
    Content type: Research article Published on:

  10. Extended-spectrum ß-lactamase-producing Enterobacteriaceae (ESBL-PE) represent a major problem in the management of nosocomial infections. However, ESBL-PE are not systematically monitored in African countries. T...

    Authors: Oumar Ouchar Mahamat, Manon Lounnas, Mallorie Hide, Yann Dumont, Abelsalam Tidjani, Kadidja Kamougam, Madina Abderrahmane, Julio Benavides, Jérôme Solassol, Anne-Laure Bañuls, Hélène jean-Pierre, Christian Carrière and Sylvain Godreuil
    Citation: BMC Infectious Diseases 2019 19:205
    Content type: Research article Published on:

  11. To evaluate the in vitro activities of plazomicin and comparator aminoglycosides and elucidate the underlying aminoglycoside resistance mechanisms among carbapenemase-producing K. pneumoniae isolates collected du...

    Authors: Irene Galani, Konstantina Nafplioti, Panagiota Adamou, Ilias Karaiskos, Helen Giamarellou and Maria Souli
    Citation: BMC Infectious Diseases 2019 19:167
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Infectious Diseases 2019 19:230

  12. Clinical characteristics (taxonomy, virulence genes and antimicrobial resistance ) of Aeromonas in isolated from extra-intestinal and intestinal infections were investigated to describe epidemiology, associated v...

    Authors: Yanyan Zhou, Li Yu, Zheng Nan, Pingping Zhang, Biao Kan, Donghui Yan and Jianrong Su
    Citation: BMC Infectious Diseases 2019 19:158
    Content type: Research article Published on:

  13. Emerging antimicrobial resistance is a significant threat to human health. However, methods for rapidly diagnosing antimicrobial resistance generally require multi-day culture-based assays. Macrolide efflux ge...

    Authors: Megan M. Nelson, Christopher L. Waldron and John R. Bracht
    Citation: BMC Infectious Diseases 2019 19:144
    Content type: Technical advance Published on:

  14. Cirrhosis-associated immune dysfunction syndrome (CAIDS) has been identified in patients with liver cirrhosis (LC), predisposing them to a wide variety of infections. In patients with LC, healthcare-associated...

    Authors: Tamara Milovanovic, Igor Dumic, Jelena Veličkovic, Milica Stojkovic Lalosevic, Vladimir Nikolic and Ivan Palibrk
    Citation: BMC Infectious Diseases 2019 19:141
    Content type: Research article Published on:

  15. Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli are responsible for severe infections worldwide. Whereas their genotypic and pathogenic characteristics are not documented in Democratic Republic...

    Authors: Leonid M. Irenge, Jerome Ambroise, Bertrand Bearzatto, Jean-François Durant, Raphaël B. Chirimwami and Jean-Luc Gala
    Citation: BMC Infectious Diseases 2019 19:137
    Content type: Research article Published on:

  16. Pyrazinamide (PZA) is an important component of first-line drugs because of its distinctive capability to kill subpopulations of persistent Mycobacterium tuberculosis (MTB). The prodrug (PZA) is converted to its ...

    Authors: Muhammad Tahir khan, Shaukat Iqbal Malik, Sajid Ali, Nayyer Masood, Tariq Nadeem, Anwar Sheed Khan and Muhammad Tanvir Afzal
    Citation: BMC Infectious Diseases 2019 19:116
    Content type: Research article Published on: