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Host microenvironment in breast cancer development

Gloria Heppner

  1. Mammary epithelial cells comprise the functional component of the normal gland and are the major target for carcinogenesis in mammary cancer. However, the stromal compartment of the normal gland and of tumors ...

    Authors: Sandra Z Haslam and Terry L Woodward
    Citation: Breast Cancer Research 2003 5:208
  2. Epithelial–mesenchymal interactions play an important role both in normal mammary gland development and during neoplastic transformation. Perturbations in the production, deposition and degradation of the extr...

    Authors: Malathy PV Shekhar, Robert Pauley and Gloria Heppner
    Citation: Breast Cancer Research 2003 5:130
  3. The epithelial–mesenchymal transition (EMT) is a developmental mechanism of crucial importance in establishing the body plan in many multicellular organisms. Several transduction pathways controlling the vario...

    Authors: Anne Vincent-Salomon and Jean Paul Thiery
    Citation: Breast Cancer Research 2003 5:101
  4. A comprehensive overview of breast cancer development and progression suggests that the process is influenced by intrinsic properties of the tumor cells, as well as by microenvironmental factors. Indeed, in br...

    Authors: A Ben-Baruch
    Citation: Breast Cancer Research 2002 5:31