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Progesterone receptors - animal models and cell signaling in breast cancer

John Lydon

  1. Progestins are included in menopausal hormone replacement therapy to counteract the increased risk for endometrial cancer associated with estrogen replacement therapy. Studies of hormone replacement therapy an...

    Authors: Catherine Schairer
    Citation: Breast Cancer Research 2002 4:244
    Content type: Review Published on:

  2. Progesterone and estradiol, and their nuclear receptors, play essential roles in the physiology of the reproductive tract, the mammary gland and the nervous system. Estrogens have traditionally been considered...

    Authors: Claudia Lanari and Alfredo A Molinolo
    Citation: Breast Cancer Research 2002 4:240
    Content type: Review Published on:

  3. A relatively small number of cells in the normal human mammary gland express receptors for oestrogen and progesterone (ER and PR), and there is almost complete dissociation between steroid receptor expression ...

    Authors: Elizabeth Anderson
    Citation: Breast Cancer Research 2002 4:197
    Content type: Review Published on:

  4. The progesterone receptor knockout mouse demonstrated progesterone's importance to parity-induced mammary tertiary branching and lobuloalveologenesis. Because early parity provides significant protection again...

    Authors: Selma Soyal, Preeti M Ismail, Jie Li, Biserka Mulac-Jericevic, Orla M Conneely and John P Lydon
    Citation: Breast Cancer Research 2002 4:191
    Content type: Review Published on:

  5. Progesterone is an essential regulator of normal female reproductive function. Its effects are mediated by two nuclear progesterone receptor (PR) proteins, PRA and PRB, which are identical except for an additi...

    Authors: J Dinny Graham and Christine L Clarke
    Citation: Breast Cancer Research 2002 4:187
    Content type: Review Published on:

  6. Progesterone, an ovarian steroid hormone, plays a key role in the development and function of the mammary gland, as it also does in the uterus and the ovary. The action of progesterone is mediated through its ...

    Authors: Xiuhua Gao and Zafar Nawaz
    Citation: Breast Cancer Research 2002 4:182
    Content type: Review Published on: