We are witnessing a dramatic shift in the foundations of mental health and psychiatry, where research into the biological underpinnings of psychopathology is becoming increasingly important. This article collection aims to focus on all areas relevant to the mood and anxiety disorders at the level of their underlying mechanisms, including but not limited to: pathophysiology, predictive risk markers, treatment predictors, individual differences and developmental trajectories of mood and anxiety disorders. We welcome further research submissions on these topics. If you would like to submit your manuscript for consideration in the series, please contact firstname.lastname@example.org.
Intolerance of uncertainty predicts fear extinction in amygdala-ventromedial prefrontal cortical circuitry
Coordination of activity between the amygdala and ventromedial prefrontal cortex (vmPFC) is important for fear-extinction learning. Aberrant recruitment of this circuitry is associated with anxiety disorders. ...
Citation: Biology of Mood & Anxiety Disorders 2015 5:4