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Coronavirus research highlights

A novel coronavirus, 2019-nCoV, has been identified as the cause of an outbreak of respiratory illness that originated in Wuhan, China, and which has spread to several other countries around the world.  Recent content from BMC and SpringerOpen journals relevant to coronavirus research, as well as additional commentary on this topic, is included below. 

BMC, as part of Springer Nature, encourages early sharing of research submitted to all our journals through preprints, and our In Review preprint service is available for many journals. We strongly urge authors submitting articles related to this emergency to BMC journals to share underlying interim and final research datasets relating to the outbreak as rapidly and widely as possible, including with public health and research communities and the WHO.

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  1. This study aims to determine the protection provided by Shenfu injection (a traditional Chinese medicine) against development of organ dysfunction in critically ill patients with coronavirus disease 2019 (COVI...

    Authors: Zong-Yu Wang, Shou-Zhi Fu, Liang Xu, Shu-Sheng Li, Ke-Jian Qian, Xian-Di He, Guo-Chao Zhu, Liang-Hai Li, Jun Zhang, Wen-Fang Li, Bing-Yu Qin, Chen-Liang Zhou and Peng-Lin Ma

    Citation: Trials 2020 21:738

    Content type: Letter

    Published on:

  2. Novel coronavirus disease 2019 presents with fever, dry cough, fatigue, and shortness of breath in most cases; however, some rare manifestations in other organs have also been reported so far.

    Authors: Maryam Heidarpour, Mehrbod Vakhshoori, Saeed Abbasi, Davood Shafie and Nima Rezaei

    Citation: Journal of Medical Case Reports 2020 14:134

    Content type: Case report

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  3. In December 2019, an outbreak of coronavirus disease (later named as COVID-19) was identified in Wuhan, China and, later on, detected in other parts of China. Our aim is to evaluate the effectiveness of the ev...

    Authors: Hui Wan, Jing-An Cui and Guo-Jing Yang

    Citation: Infectious Diseases of Poverty 2020 9:116

    Content type: Research Article

    Published on:

  4. Caledonian Stadium, the main mass temporary shelter for homeless people in the City of Tshwane, was created as a local response to the imperatives of the novel coronavirus disease (COVID-19) National State of ...

    Authors: Tessa S. Marcus, Jan Heese, Andrew Scheibe, Shaun Shelly, Sasha X. Lalla and Jannie F. Hugo

    Citation: Harm Reduction Journal 2020 17:60

    Content type: Research

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  5. The coronavirus disease 2019 (COVID-19) pandemic may raise unique challenges for individuals with experience of eating disorders. Many factors have potential for detrimental impacts on psychological wellbeing ...

    Authors: Dawn Branley-Bell and Catherine V. Talbot

    Citation: Journal of Eating Disorders 2020 8:44

    Content type: Research article

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  6. The emerging infectious disease, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses a serious threat in China and worldwide. Challenged by this se...

    Authors: Tie-Long Xu, Mei-Ying Ao, Xu Zhou, Wei-Feng Zhu, He-Yun Nie, Jian-He Fang, Xin Sun, Bin Zheng and Xiao-Fan Chen

    Citation: Infectious Diseases of Poverty 2020 9:115

    Content type: Short Report

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  7. The 2019 novel coronavirus disease (COVID-19) has been found in more than 200 countries worldwide since December, 2019. In China, a major reason for the rapid transmission of the COVID-19 in early stage of the...

    Authors: Zi-Han Liu, Yan-Jie Zhao, Yuan Feng, Qinge Zhang, Bao-Liang Zhong, Teris Cheung, Brian J. Hall and Yu-Tao Xiang

    Citation: Globalization and Health 2020 16:75

    Content type: Commentary

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  8. In less than 20 years, three deadly coronaviruses, SARS-CoV, MERS-CoV and SARS-CoV-2, have emerged in human population causing hundreds to hundreds of thousands of deaths. Other coronaviruses are causing epizo...

    Authors: Laure Perrin-Cocon, Olivier Diaz, Clémence Jacquemin, Valentine Barthel, Eva Ogire, Christophe Ramière, Patrice André, Vincent Lotteau and Pierre-Olivier Vidalain

    Citation: Journal of Translational Medicine 2020 18:319

    Content type: Review

    Published on:

  9. COVID 19-related quarantine led to a sudden and radical lifestyle changes, in particular in eating habits. Objectives of the study were to investigate the effect of quarantine on sleep quality (SQ) and body mass ...

    Authors: Luigi Barrea, Gabriella Pugliese, Lydia Framondi, Rossana Di Matteo, Daniela Laudisio, Silvia Savastano, Annamaria Colao and Giovanna Muscogiuri

    Citation: Journal of Translational Medicine 2020 18:318

    Content type: Research

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  10. The COVID-19 pandemic has exerted considerable impact on public mental health globally. With the pandemic rapidly rising in sub-Saharan Africa including Kenya, there is need to provide evidence to guide the me...

    Authors: Florence Jaguga and Edith Kwobah

    Citation: International Journal of Mental Health Systems 2020 14:68

    Content type: Review

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  11. Healthcare resources have been strained to previously unforeseeable limits as a result of the COVID-19 pandemic of 2020. This has prompted the emergence of critical just-in-time COVID-19 education, including r...

    Authors: Mirette Dubé, Alyshah Kaba, Theresa Cronin, Sue Barnes, Tara Fuselli and Vincent Grant

    Citation: Advances in Simulation 2020 5:22

    Content type: Innovation

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  12. Azithromycin is an orally active synthetic macrolide antibiotic with a wide range of anti-bacterial, anti-inflammatory and antiviral properties. It is a safe, inexpensive, generic licenced drug available world...

    Authors: Timothy S. C. Hinks, Vicki S. Barber, Joanna Black, Susan J. Dutton, Maisha Jabeen, James Melhorn, Najib M Rahman, Duncan Richards, Daniel Lasserson, Ian D. Pavord and Mona Bafadhel

    Citation: Trials 2020 21:718

    Content type: Study protocol

    Published on:

  13. There are no specific generally accepted therapies for the coronavirus disease 2019 (COVID-19). The full spectrum of COVID-19 ranges from asymptomatic disease to mild respiratory tract illness to severe pneumo...

    Authors: Jesús Villar, José M. Añón, Carlos Ferrando, Gerardo Aguilar, Tomás Muñoz, José Ferreres, Alfonso Ambrós, César Aldecoa, Fernando Suárez-Sipmann, Kevin E. Thorpe, Peter Jüni and Arthur S. Slutsky

    Citation: Trials 2020 21:717

    Content type: Study protocol

    Published on:

  14. In the rapidly evolving coronavirus disease 2019 (COVID-19) outbreak, inherent literature has been increasing at an impressive rate. Such a dynamic scenario imposes the necessity to define a new framework for ...

    Authors: Maddalena Barba, Eriseld Krasniqi, Gennaro Ciliberto and Patrizia Vici

    Citation: Journal of Translational Medicine 2020 18:315

    Content type: Commentary

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  15. As of 13 July 2020, 12.9 million COVID-19 cases have been reported worldwide. Prior studies have demonstrated that local socioeconomic and built environment characteristics may significantly contribute to vira...

    Authors: Christopher Scarpone, Sebastian T. Brinkmann, Tim Große, Daniel Sonnenwald, Martin Fuchs and Blake Byron Walker

    Citation: International Journal of Health Geographics 2020 19:32

    Content type: Research

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  16. Available studies are lacking in analysis of baseline demographics and hospital presentation of patients at risk of expiring due to coronavirus disease 2019 (COVID-19), particularly Black American patients. We...

    Authors: James Andrew McCracken, Mohamed Nakeshbandi, Jeffrey Arace, Wayne J. Riley and Roopali Sharma

    Citation: Translational Medicine Communications 2020 5:12

    Content type: Research

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  17. Medical care workers experienced unprecedented levels of workload and pressure since the outbreak of coronavirus disease 2019 (COVID-19). Little is known about its exact impact on medical care workers and rela...

    Authors: Ming-Yu Si, Xiao-You Su, Yu Jiang, Wen-Jun Wang, Xiao-Fen Gu, Li Ma, Jing Li, Shao-Kai Zhang, Ze-Fang Ren, Ran Ren, Yuan-Li Liu and You-Lin Qiao

    Citation: Infectious Diseases of Poverty 2020 9:113

    Content type: Research Article

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  18. The outbreak of coronavirus disease 2019 (COVID-19) had spread worldwide. Although the world has intensively focused on the epidemic center during this period of time, it is imperative to emphasize that more a...

    Authors: Ru-Jun Liao, Chun-Nong Ji-Ke, Tao Zhang, Qiang Liao, Ling Li, Tian-Yu Zhu and Shao-Yong Bian

    Citation: Infectious Diseases of Poverty 2020 9:112

    Content type: Case Study

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  19. Psychological distress is highly prevalent among migraineurs during public health emergencies. The coronavirus disease 2019 (nCOV-2019) has created mass panic in China due to its highly contagious by contact a...

    Authors: Mengmeng Ma, Jinghuan Fang, Changling Li, Jiajia Bao, Yang Zhang, Ning Chen, Jian Guo and Li He

    Citation: The Journal of Headache and Pain 2020 21:100

    Content type: Research article

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  20. The German government has made it mandatory to wear respiratory masks covering mouth and nose (MNC) as an effective strategy to fight SARS-CoV-2 infections. In many countries, this directive has been extended ...

    Authors: Christiane Matuschek, Friedrich Moll, Heiner Fangerau, Johannes C. Fischer, Kurt Zänker, Martijn van Griensven, Marion Schneider, Detlef Kindgen-Milles, Wolfram Trudo Knoefel, Artur Lichtenberg, Balint Tamaskovics, Freddy Joel Djiepmo-Njanang, Wilfried Budach, Stefanie Corradini, Dieter Häussinger, Torsten Feldt…

    Citation: European Journal of Medical Research 2020 25:32

    Content type: Review

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  21. Measures aiming at containing the Coronavirus disease 2019 (COVID-19) include isolation, social distancing, and quarantine. Quarantine and other lockdown instruments show promise in reducing the number of COVI...

    Authors: Eszter Füzéki, David A. Groneberg and Winfried Banzer

    Citation: Journal of Occupational Medicine and Toxicology 2020 15:25

    Content type: Review

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  22. The coronavirus disease 2019 (COVID-19) epidemic met coincidentally with massive migration before Lunar New Year in China in early 2020. This study is to investigate the relationship between the massive migrat...

    Authors: Wen-Yu Song, Pan Zang, Zhong-Xing Ding, Xin-Yu Fang, Li-Guo Zhu, Ya Zhu, Chang-Jun Bao, Feng Chen, Ming Wu and Zhi-Hang Peng

    Citation: Infectious Diseases of Poverty 2020 9:109

    Content type: Research Article

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  23. As the outbreak of coronavirus disease 2019 (COVID-19) has progressed, computed tomography has emerged as an integral part of the diagnosis alongside reverse transcriptase–polymerase chain reaction assays. Fre...

    Authors: Mohsin Sheraz Mughal, Rameez Rehman, Ramy Osman, Nathan Kan, Hasan Mirza and Margaret H. Eng

    Citation: Journal of Medical Case Reports 2020 14:124

    Content type: Case report

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  24. Healthcare workers (HCWs) are at particular risk during pandemics and epidemics of highly virulent diseases with significant morbidity and case fatality rate. These diseases include severe acute respiratory sy...

    Authors: Ana Licina, Andrew Silvers and Rhonda L. Stuart

    Citation: Systematic Reviews 2020 9:173

    Content type: Systematic review update

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  25. The first reports of the Chinese experience in the management of newborns of mothers with SARS-CoV 2 infection did not recommend mother-baby contact or breastfeeding. At present, the most important Internation...

    Authors: Augusto Pereira, Sara Cruz-Melguizo, Maria Adrien, Lucia Fuentes, Eugenia Marin, Azul Forti and Tirso Perez-Medina

    Citation: International Breastfeeding Journal 2020 15:69

    Content type: Research

    Published on:

  26. COVID-19 pandemia is affecting Countries worldwide with a gendered death excess as being a male represents, especially in the 50–69 years age group, an unfavourable factor. Females are constitutionally prone t...

    Authors: Lorenzo Salvati, Benedetta Biagioni, Emanuele Vivarelli and Paola Parronchi

    Citation: Clinical and Molecular Allergy 2020 18:14

    Content type: Review

    Published on:

  27. Obesity and steatosis are associated with COVID-19 severe pneumonia. Elevated levels of pro-inflammatory cytokines and reduced immune response are typical of these patients. In particular, adipose tissue is th...

    Authors: Antonino De Lorenzo, Maria Grazia Tarsitano, Carmela Falcone, Laura Di Renzo, Lorenzo Romano, Sebastiano Macheda, Anna Ferrarelli, Demetrio Labate, Marco Tescione, Federico Bilotta and Paola Gualtieri

    Citation: Journal of Translational Medicine 2020 18:299

    Content type: Research

    Published on:

  28. The severe acute respiratory syndrome virus SARS-CoV-2, a close relative of the SARS-CoV virus, is the cause of the recent COVID-19 pandemic affecting, to date, over 14 million individuals across the globe and...

    Authors: Nophar Geifman and Anthony D. Whetton

    Citation: Journal of Translational Medicine 2020 18:297

    Content type: Research

    Published on:

  29. The World Health Organization declared on March 11, 2020, that the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) has escalated from epidemic into pandemic. As the initial outbreak ...

    Authors: Yuxi Li, Juan Li, Dongling Zhong, Yue Zhang, Yonggang Zhang, Yan Guo, Mike Clarke and Rongjiang Jin

    Citation: Systematic Reviews 2020 9:170

    Content type: Protocol

    Published on:

  30. Disabled people are particularly exposed to the risks of COVID-19, as well as to the measures taken to address it, and their impact. The aim of the study was to examine the disability-inclusiveness of governme...

    Authors: Dikaios Sakellariou, Ana Paula Serrata Malfitano and Elena S. Rotarou

    Citation: International Journal for Equity in Health 2020 19:131

    Content type: Research

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  31. The number of coronavirus disease 2019 (COVID-19) cases has rapidly increased all over the world. Specific information about immunity in non-survivors with COVID-19 is scarce. This study aimed to analyse the c...

    Authors: Yang Zhao, Han-Xiang Nie, Ke Hu, Xiao-Jun Wu, Yun-Ting Zhang, Meng-Mei Wang, Tao Wang, Zhi-Shui Zheng, Xiao-Chen Li and Shao-Lin Zeng

    Citation: Infectious Diseases of Poverty 2020 9:108

    Content type: Research Article

    Published on:

  32. More severe cases of COVID- 19 are more likely to be hospitalized and around one-fifth, needing ICU admission. Understanding the common laboratory features of COVID-19 in more severe cases versus non-severe pa...

    Authors: Sulmaz Ghahramani, Reza Tabrizi, Kamran B. Lankarani, Seyyed Mohammad Amin Kashani, Shahla Rezaei, Nazanin Zeidi, Maryam Akbari, Seyed Taghi Heydari, Hamed Akbari, Peyman Nowrouzi-Sohrabi and Fariba Ahmadizar

    Citation: European Journal of Medical Research 2020 25:30

    Content type: Review

    Published on:

  33. Stage 1: To evaluate the safety and efficacy of candidate agents as add-on therapies to standard of care (SoC) in patients hospitalised with COVID-19 in a screening stage.

    Authors: Tom Wilkinson, Rupert Dixon, Clive Page, Miles Carroll, Gareth Griffiths, Ling-Pei Ho, Anthony De Soyza, Timothy Felton, Keir E. Lewis, Karen Phekoo, James D. Chalmers, Anthony Gordon, Lorcan McGarvey, Jillian Doherty, Robert C. Read, Manu Shankar-Hari…

    Citation: Trials 2020 21:691

    Content type: Letter

    Published on:

  34. Covid-19 morbidity and mortality are associated with a dysregulated immune response. Tools are needed to enhance existing immune profiling capabilities in affected patients. Here we aimed to develop an approac...

    Authors: Darawan Rinchai, Basirudeen Syed Ahamed Kabeer, Mohammed Toufiq, Zohreh Tatari-Calderone, Sara Deola, Tobias Brummaier, Mathieu Garand, Ricardo Branco, Nicole Baldwin, Mohamed Alfaki, Matthew C. Altman, Alberto Ballestrero, Matteo Bassetti, Gabriele Zoppoli, Andrea De Maria, Benjamin Tang…

    Citation: Journal of Translational Medicine 2020 18:291

    Content type: Research

    Published on:

  35. Coronavirus disease 2019 (COVID-19) is spreading fast all around the world with more than fourteen millions of detected infected cases and more than 600.000 deaths by 20th July 2020. While scientist are workin...

    Authors: Alberto Sainz-Cort and Joost H. Heeroma

    Citation: Journal of Cannabis Research 2020 2:23

    Content type: Commentary

    Published on:

  36. Coronavirus disease 2019 (COVID-19) is a new global public health emergency. The therapeutic benefits of Cold‒Damp Plague Formula (CDPF) against COVID-19, which was used to treat “cold‒dampness stagnation in t...

    Authors: Lin Han, Xiu-Xiu Wei, Yu-Jiao Zheng, Li-Li Zhang, Xin-Miao Wang, Hao-Yu Yang, Xu Ma, Lin-Hua Zhao and Xiao-Lin Tong

    Citation: Chinese Medicine 2020 15:78

    Content type: Research

    Published on:

  37. The health crisis caused by COVID-19 has led many countries to opt for social quarantine of the population. During this quarantine, communication systems have been characterized by disintermediation, the accelera...

    Authors: Álex Escolà-Gascón, Francesc-Xavier Marín, Jordi Rusiñol and Josep Gallifa

    Citation: Globalization and Health 2020 16:72

    Content type: Research

    Published on:

  38. The aim of this study is to assess the efficacy of the use of pre-exposure prophylaxis (PrEP) with hydroxychloroquine against placebo in healthcare workers with high risk of severe acute respiratory syndrome c...

    Authors: Berta Grau-Pujol, Daniel Camprubí, Helena Marti-Soler, Marc Fernández-Pardos, Caterina Guinovart and Jose Muñoz

    Citation: Trials 2020 21:688

    Content type: Letter

    Published on:

  39. Coronavirus disease 2019 (COVID-19) is a new respiratory and systemic disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The purpose of the present study was to investiga...

    Authors: Li-Da Chen, Zhen-Yu Zhang, Xiao-Jie Wei, Yu-Qing Cai, Weng-Zhen Yao, Ming-Hui Wang, Qiu-Fen Huang and Xiao-Bin Zhang

    Citation: Respiratory Research 2020 21:201

    Content type: Research

    Published on:

  40. By mid-May 2020, there were over 1.5 million cases of (SARS-CoV-2) or COVID-19 across the U.S. with new confirmed cases continuing to rise following the re-opening of most states. Prior studies have focused ma...

    Authors: Yelena Rozenfeld, Jennifer Beam, Haley Maier, Whitney Haggerson, Karen Boudreau, Jamie Carlson and Rhonda Medows

    Citation: International Journal for Equity in Health 2020 19:126

    Content type: Research

    Published on:

  41. Headache is one of the most frequent neurologic manifestations in COVID-19. We aimed to analyze which symptoms and laboratory abnormalities were associated with the presence of headache and to evaluate if pati...

    Authors: Javier Trigo, David García-Azorín, Álvaro Planchuelo-Gómez, Enrique Martínez-Pías, Blanca Talavera, Isabel Hernández-Pérez, Gonzalo Valle-Peñacoba, Paula Simón-Campo, Mercedes de Lera, Alba Chavarría-Miranda, Cristina López-Sanz, María Gutiérrez-Sánchez, Elena Martínez-Velasco, María Pedraza, Álvaro Sierra, Beatriz Gómez-Vicente…

    Citation: The Journal of Headache and Pain 2020 21:94

    Content type: Research article

    Published on:

  42. The COVID pandemic has been devastating for not only its direct impact on lives, physical health, socio-economic status of individuals, but also for its impact on mental health. Some individuals are affected p...

    Authors: Pallab K. Maulik, Graham Thornicroft and Shekhar Saxena

    Citation: International Journal of Mental Health Systems 2020 14:57

    Content type: Debate

    Published on:

  43. COVID-19 has taken the world by surprise; even the most sophisticated healthcare systems have been unable to cope with the volume of patients and lack of resources. Yet the gradual spread of the virus in Leban...

    Authors: Zavi Lakissian, Rami Sabouneh, Rida Zeineddine, Joe Fayad, Rim Banat and Rana Sharara-Chami

    Citation: Advances in Simulation 2020 5:15

    Content type: Research

    Published on:

  44. The novel coronavirus disease 2019 (COVID-19) pandemic is a global crisis, challenging healthcare systems worldwide. Many patients present with a remarkable disconnect in rest between profound hypoxemia yet wi...

    Authors: Sebastiaan Dhont, Eric Derom, Eva Van Braeckel, Pieter Depuydt and Bart N. Lambrecht

    Citation: Respiratory Research 2020 21:198

    Content type: Review

    Published on:

  45. The outbreak of 2019 coronavirus disease (COVID-19) could increase the risk of depression. However, epidemiological data on outbreak-associated depressive morbidity of female adolescents are not available. Thi...

    Authors: Jiaojiao Zhou, Xiaofei Yuan, Han Qi, Rui Liu, Yaqiong Li, Huanhuan Huang, Xu Chen and Gang Wang

    Citation: Globalization and Health 2020 16:69

    Content type: Research

    Published on:

  46. In an effort to prevent infants being infected with SARS-CoV-2, some governments, professional organisations, and health facilities are instituting policies that isolate newborns from their mothers and otherwi...

    Authors: Karleen Gribble, Roger Mathisen, Mija-tesse Ververs and Anna Coutsoudis

    Citation: International Breastfeeding Journal 2020 15:67

    Content type: Commentary

    Published on: