Guest editor: Jay Shendure
Genome Medicine presents a special issue on ‘From genomics to disease mechanisms’. Now that sequencing has moved into the clinic, researchers and clinicians are working together to understand the genomic mechanisms that underlie disease. We are moving from an era of association studies to functional studies that are beginning to reveal the cause of the clinical phenotype. A multi-disciplinary and multi-omic approach will be required to explain how genotypes give rise to phenotypes.
This collection of articles has not been sponsored and articles have undergone the journal’s standard peer-review process. The Guest Editor declares no competing interests.