The microbiome plays a pivotal role for the proper function of the gastrointestinal and hepatobiliary system. Its composition is influenced by many factors, including diet, lifestyle, medications, and environment. The gut microbiota indirectly acts as playmaker for interaction between precision medicine and direct bacterial productions and their mediation with human immunity and energy homeostasis. Maintaining a healthy gut microbiome is crucial for overall health, as imbalances within the gut microbiome, have been correlated with various health conditions, such as inflammatory bowel disease (IBD), clostridioides difficile infection (CDI), nonalcoholic fatty liver disease (NAFLD), hepatic encephalopathy and cholangitis. Precision nutrition can support gastrointestinal and hepatobiliary health by promoting a balanced and nutrient-dense diet that supports the growth and diversity of the microbiome. By tailoring nutrition plans to an individual`s distinctive needs and genetic characteristics, precision nutrition can be an effective approach for promoting gastrointestinal and hepatobiliary health.
This special collection aims to collate articles on the microbiome in the context of gastrointestinal and hepatobiliary pathophysiology and the latest insights into how precision nutrition can optimize health and prevent or treat disease.
Potential topics include but are not limited to the following:
• The effect of precision nutrition on the gut microbiome and the development and progression of inflammatory bowel disease (IBD).
• The role of personalized nutrition interventions in the prevention and treatment of gastroesophageal reflux disease (GERD).
• The impact of personalized diets on gut microbiome composition and diversity in patients with irritable bowel syndrome (IBS).
• The relationship between the gut microbiome and nutrient absorption in patients with malabsorption disorders such as celiac disease.
• The effectiveness of personalized nutrition interventions in improving gut microbiome diversity and reducing chronic inflammation in patients with gastrointestinal disorders.
• The use of precision nutrition in the prevention and treatment of gastrointestinal cancers.
• The impact of personalized nutrition interventions on gut microbiome composition and function in patients undergoing gastrointestinal surgery.
• The role of the gut microbiome in the metabolism of medications used to treat gastrointestinal disorders.
• The relationship between the gut microbiome and liver disease, including nonalcoholic fatty liver disease (NAFLD) and cirrhosis.
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