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Malaria Elimination Demonstration Project, Mandla, India.

The Malaria Elimination Demonstration Project (MEDP) was undertaken in 1233 villages of district Mandla, in central Indian State of Madhya Pradesh.  This project is a Public-Private-Partnership between the Indian Council of Medical Research, Ministry of Health and Family Welfare, the Government of the State of Madhya Pradesh, and the Foundation for Disease Elimination and Control of India (a not-for-profit entity created by Sun Pharmaceutical Industries Limited for conducting public health programmes).  


The MEDP employs field-tested and proven principles and strategies for malaria elimination with context specific modifications. The case management aspect of elimination is based on the T4 strategy (tracking fever cases by active surveillance), testing by national programme-approved RDTs, treating RDT-positive individuals following national guidelines using ACT and other approved anti-malarials, and testing the efficacy of treatment. The vector control strategy involves provision of LLIN, IRS and minor engineering. The project has developed a mobile surveillance tool that captures malaria testing and treatment data as well as attendance of staff and supply chain requirements of the project. Information, Education and Communication tools were developed and deployed, incorporating messages from the field staff and communities. The staff deployed for the project is from local communities, trained before and during the project to monitor needs assessment and gaps in knowledge and learnings.

This Thematic Series in Malaria Journal presents various components of the project, including inter-sectoral coordination, mobile surveillance tools, behaviour change communication, capacity building, entomology, disease surveillance and case management, mass screenings and treatment, training and assessment.

  1. Despite the progress made in this decade towards malaria elimination, it remains a significant public health concern in India and many other countries in South Asia and Asia Pacific region. Understanding the h...

    Authors: Mrigendra P. Singh, Harsh Rajvanshi, Praveen K. Bharti, Anup R. Anvikar and Altaf A. Lal
    Citation: Malaria Journal 2024 23:50
  2. Resistance against artemisinin-based combination therapy is one of the challenges to malaria control and elimination globally. Mutations in different genes (Pfdhfr, Pfdhps, Pfk-13 and Pfmdr1) confer resistance to...

    Authors: Akansha Singh, Mrigendra P. Singh, Nazia Anwar Ali, Rajan Poriya, Harsh Rajvanshi, Sekh Nisar, Sneha Bhandari, Ram S. Sahu, Himanshu Jayswar, Ashok K. Mishra, Aparup Das, Harpreet Kaur, Anup R. Anvikar, Ananias A Escalante, Altaf A. Lal and Praveen K. Bharti
    Citation: Malaria Journal 2023 22:375
  3. Global malaria cases rose by 14 million, and deaths by 69,000, in 2020. In India, a 46% decline has been reported between 2020 and 2019. In 2017, the Malaria Elimination Demonstration Project conducted a needs...

    Authors: Mrigendra P. Singh, Harsh Rajvanshi, Sekh Nisar, Akansha Singh, Himanshu Jayswar, Srinath Singh, R. K. Mehra, S. K. Shrivastava, Ram Shankar Sahu, Brajesh Patel, Ramji Bhalavi, Kalyan B. Saha, Ravendra K. Sharma, Ashok K. Mishra, Harpreet Kaur, Aparup Das…
    Citation: Malaria Journal 2023 22:62
  4. Compared to 2017, India achieved a significant reduction in malaria cases in 2020. Madhya Pradesh (MP) is a tribal dominated state of India with history of high malaria burden in some districts. District Mandl...

    Authors: Mrigendra P. Singh, Harsh Rajvanshi, Praveen K. Bharti, Himanshu Jayswar, Srinath Singh, R. K. Mehra, Manoj Pandey, Ram Shankar Sahu, Brajesh Patel, Ramji Bhalavi, Sekh Nisar, Harpreet Kaur, Aparup Das, Davidson H. Hamer and Altaf A. Lal
    Citation: Malaria Journal 2023 22:45
  5. Mass screening and treatment (MSaT) aims at reducing the spread of malaria in communities by identifying and treating infected persons regardless of the symptoms. This study was conducted to identify and treat...

    Authors: Akansha Singh, Harsh Rajvanshi, Mrigendra P. Singh, Sneha Bhandari, Sekh Nisar, Rajan Poriya, Vinay Telasey, Himanshu Jayswar, Ashok K. Mishra, Aparup Das, Harpreet Kaur, Altaf A. Lal and Praveen K. Bharti
    Citation: Malaria Journal 2022 21:395
  6. The utilization and impact of the healthcare services depend on the perceived quality, appropriateness, ease of availability, and cost of the services. This study aimed to understand the community's perception...

    Authors: Mrigendra P. Singh, Harsh Rajvanshi, Praveen K. Bharti, Aparup Das, Vikesh Thakre, Himanshu Jayswar, Ram Shankar Sahu, Vinay K. Telasey and Altaf A. Lal
    Citation: Malaria Journal 2022 21:368
  7. Low-density malaria infections (LDMI) are defined as infections that are missed by the rapid diagnostic test (RDT) and/or microscopy which can lead to continued transmission and poses a challenge in malaria el...

    Authors: Akansha Singh, Mrigendra P. Singh, Sneha Bhandari, Harsh Rajvanshi, Sekh Nisar, Vinay Telasey, Himanshu Jayswar, Ashok K. Mishra, Aparup Das, Harpreet Kaur, Altaf A. Lal and Praveen K. Bharti
    Citation: Malaria Journal 2022 21:341
  8. The capacity of the field staff to conduct activities related to disease surveillance, case management, and vector control has been one of the key components for successfully achieving malaria elimination. Ind...

    Authors: Harsh Rajvanshi, Praveen K. Bharti, Ravendra K. Sharma, Sekh Nisar, Kalyan B. Saha, Himanshu Jayswar, Ashok K. Mishra, Aparup Das, Harpreet Kaur and Altaf A. Lal
    Citation: Malaria Journal 2022 21:18
  9. Changes in social, belief, and behavioural practices are essential for the success of any public health delivery programme. In the planning stages of the Malaria Elimination Demonstration Project (MEDP), prior...

    Authors: Harsh Rajvanshi, Kalyan B. Saha, Ravendra K. Sharma, Praveen K. Bharti, Sekh Nisar, Himanshu Jayswar, Ashok K. Mishra, Man Mohan Shukla, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal
    Citation: Malaria Journal 2021 20:354
  10. The Government of Madhya Pradesh employed Indoor Residual Spraying (IRS) with alpha-cypermethrin synthetic pyrethroids in sub-centres with Annual Parasite Incidence (API) from 2 to 4.99. In sub-centres with AP...

    Authors: Ashok K. Mishra, Sekh Nisar, Harsh Rajvanshi, Praveen K. Bharti, Kalyan B. Saha, Man Mohan Shukla, Ravendra K. Sharma, Himanshu Jayswar, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal
    Citation: Malaria Journal 2021 20:101
  11. Malaria Elimination Demonstration Project (MEDP) was started as a Public-Private-Partnership between the Indian Council of Medical Research through National Institute of Research in Tribal Health, Govt. of Mad...

    Authors: Harsh Rajvanshi, Praveen K. Bharti, Sekh Nisar, Himanshu Jayswar, Ashok K. Mishra, Ravendra K. Sharma, Kalyan B. Saha, Man Mohan Shukla, Suman L. Wattal, Aparup Das, Harpreet Kaur, Anupkumar R. Anvikar, Azadar Khan, Nilima Kshirsagar, Aditya P. Dash and Altaf A. Lal
    Citation: Malaria Journal 2021 20:98
  12. Health care technologies are now offering accountability, quality, robustness, and accuracy in disease surveillance and health care delivery programmes. With the advent of mobile hand-held devices, these techn...

    Authors: Harsh Rajvanshi, Yashpal Jain, Nidhi Kaintura, Chaitanya Soni, Raja Chandramohan, Ramanathan Srinivasan, Vinay Telasey, Praveen K. Bharti, Deepak Jain, Mangeshi Surve, Sachin Saxena, Vilas Gangamwar, M. S. Anand and Altaf A. Lal
    Citation: Malaria Journal 2021 20:91
  13. The role of Accredited Social Health Activist (ASHA) in the health care delivery services at the periphery level is crucial for achieving disease prevention, control and elimination goals. The objective of th...

    Authors: Harsh Rajvanshi, Kalyan B. Saha, Man Mohan Shukla, Sekh Nisar, Himanshu Jayswar, Ashok K. Mishra, Ravendra K. Sharma, Praveen K. Bharti, Nishant Saxena, Arvind Verma, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal
    Citation: Malaria Journal 2021 20:78
  14. The Malaria Elimination Demonstration Project (MEDP) maintained a workforce of 235 Village Malaria Workers (VMWs) and 25 Malaria Field Coordinators (MFCs) to conduct disease surveillance, case management, IEC/...

    Authors: Harsh Rajvanshi, Sekh Nisar, Praveen K. Bharti, Himanshu Jayswar, Ashok K. Mishra, Ravendra K. Sharma, Kalyan B. Saha, Man Mohan Shukla, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal
    Citation: Malaria Journal 2021 20:27
  15. Malaria is known as a disease of poverty because of its dominance in poverty-stricken areas. Madhya Pradesh state in central India is one of the most vulnerable states for malaria morbidity and mortality. Soci...

    Authors: Ravendra K. Sharma, Harsh Rajvanshi, Praveen K. Bharti, Sekh Nisar, Himanshu Jayswar, Ashok K. Mishra, Kalyan B. Saha, Man Mohan Shukla, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal
    Citation: Malaria Journal 2021 20:7
  16. Understanding of malaria vector density, distribution, insecticide resistance, vector incrimination, infection status, and identification of sibling species are some of the essential components of vector contr...

    Authors: Ashok K. Mishra, Praveen K. Bharti, Anup Vishwakarma, Sekh Nisar, Harsh Rajvanshi, Ravendra K. Sharma, Kalyan B. Saha, Man Mohan Shukla, Himanshu Jayswar, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal
    Citation: Malaria Journal 2020 19:447
  17. In the past decade substantial reduction in malaria morbidity and mortality has been observed through well-implemented case management and vector control strategies. India has also achieved a significant reduc...

    Authors: Harsh Rajvanshi, Praveen K. Bharti, Sekh Nisar, Yashpal Jain, Himanshu Jayswar, Ashok K. Mishra, Ravendra K. Sharma, Kalyan B. Saha, Man Mohan Shukla, Aparup Das, Harpreet Kaur, Suman L. Wattal, Neeru Singh and Altaf A. Lal
    Citation: Malaria Journal 2020 19:410
  18. Many malaria endemic countries are heading towards malaria elimination through the use of case management and vector control strategies, which employ surveillance, improving access to early diagnosis, prompt t...

    Authors: Praveen K. Bharti, Harsh Rajvanshi, Sekh Nisar, Himanshu Jayswar, Kalyan B. Saha, Man Mohan Shukla, Ashok K. Mishra, Ravendra K. Sharma, Aparup Das, Harpreet Kaur, Suman L. Wattal and Altaf A. Lal
    Citation: Malaria Journal 2020 19:339