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From neuroscience to neuro-rehabilitation: Transferring basic neuroscientific principles from laboratory to bedside

Edited by: Alexander Koenig

An article collection in Journal of NeuroEngineering and Rehabilitation

Several new approaches for treatment of central nervous system (CNS) disorders have been successful in the laboratory setting, including the use of rehabilitation training strategies, which are often combined with electrical and/or pharmacological modulation of spinal locomotor circuitries to improve functional outcomes in people living with CNS impairment. This thematic series presents some of the current work that bridges the gap from basic science in a laboratory setting to clinical application. The articles represent a cross section of cutting edge approaches with the goal of transferring basic neuroscience principles from the laboratory to the proverbial "bedside".

This collection of articles has not been sponsored and articles have undergone the journal's standard peer-review process overseen by the Editor-in-Chief and Associate Editors. The Editor-in-Chief and Associate Editors declare no competing interests.

View all article collections published in Journal of NeuroEngineering and Rehabilitation

  1. Learning of a visuomotor task not only leads to changes in motor performance but also improves proprioceptive function of the trained joint/limb system. Such sensorimotor learning may show intra-joint transfer...

    Authors: Huiying Zhu, Yizhao Wang, Naveen Elangovan, Leonardo Cappello, Giulio Sandini, Lorenzo Masia and Jürgen Konczak
    Citation: Journal of NeuroEngineering and Rehabilitation 2023 20:143
    Content type: Research Published on:

  2. Concurrent transcranial magnetic stimulation and electroencephalography (TMS-EEG) recording provides information on both intracortical reorganization and networking, and that information could yield new insigh...

    Authors: Zhongfei Bai, Jack Jiaqi Zhang and Kenneth N. K. Fong
    Citation: Journal of NeuroEngineering and Rehabilitation 2023 20:100
    Content type: Research Published on:

  3. Multiple studies have corroborated the restoration of volitional motor control after motor-complete spinal cord injury (SCI) through the use of epidural spinal cord stimulation (eSCS), but rigorous quantitativ...

    Authors: Rajat Emanuel Singh, Aliya Ahmadi, Ann M. Parr, Uzma Samadani, Andrei V. Krassioukov, Theoden I. Netoff and David P. Darrow
    Citation: Journal of NeuroEngineering and Rehabilitation 2023 20:59
    Content type: Research Published on:

  4. In clinical and research settings, hand dexterity is often assessed as finger individuation, or the ability to move one finger at a time. Despite its clinical importance, there is currently no standardized, su...

    Authors: Brian J. Conway, Léon Taquet, Timothy F. Boerger, Sarah C. Young, Kate B. Krucoff, Brian D. Schmit and Max O. Krucoff
    Citation: Journal of NeuroEngineering and Rehabilitation 2023 20:48
    Content type: Research Published on:

  5. Several new approaches for treatment of Central Nervous System (CNS) disorders are currently under investigation, including the use of rehabilitation training strategies, which are often combined with electric...

    Authors: Alexander Koenig, Andreas Luft and Iahn Cajigas
    Citation: Journal of NeuroEngineering and Rehabilitation 2013 10:6
    Content type: Editorial Published on:

  7. Brain-computer interfaces (BCIs) were recently recognized as a method to promote neuroplastic effects in motor rehabilitation. The core of a BCI is a decoding stage by which signals from the brain are classifi...

    Authors: Raphael Zimmermann, Laura Marchal-Crespo, Janis Edelmann, Olivier Lambercy, Marie-Christine Fluet, Robert Riener, Martin Wolf and Roger Gassert
    Citation: Journal of NeuroEngineering and Rehabilitation 2013 10:4
    Content type: Research Published on:

  8. Robot-aided gait training is an emerging clinical tool for gait rehabilitation of neurological patients. This paper deals with a novel method of offering gait assistance, using an impedance controlled exoskele...

    Authors: Bram Koopman, Edwin HF van Asseldonk and Herman van der Kooij
    Citation: Journal of NeuroEngineering and Rehabilitation 2013 10:3
    Content type: Research Published on:

  9. Stimulation of the spinal cord has been shown to have great potential for improving function after motor deficits caused by injury or pathological conditions. Using a wide range of animal models, many studies ...

    Authors: Parag Gad, Jaehoon Choe, Mandheerej Singh Nandra, Hui Zhong, Roland R Roy, Yu-Chong Tai and V Reggie Edgerton
    Citation: Journal of NeuroEngineering and Rehabilitation 2013 10:2
    Content type: Research Published on:

    The Erratum to this article has been published in Journal of NeuroEngineering and Rehabilitation 2015 12:33

  10. Repetitive task practice is argued to drive neural plasticity following stroke. However, current evidence reveals that hemiparetic weakness impairs the capacity to perform, and practice, movements appropriatel...

    Authors: Carolynn Patten, Elizabeth G Condliffe, Christine A Dairaghi and Peter S Lum
    Citation: Journal of NeuroEngineering and Rehabilitation 2013 10:1
    Content type: Research Published on: