Call for papers - Regulation of gene expression through RNA

Guest Editors

Marco Mangone, PhD, Arizona State University, USA
Gian Gaetano Tartaglia, PhD, Istituto Italiano di Tecnologia (IIT), Italy

Submission Status: Open | Submission Deadline: 10 October 2024

BMC Biology is calling for submissions to our Collection on Regulation of gene expression through RNA. Forms of RNA-mediated regulation include the role of small RNAs in gene silencing, function modulation via RNA binding proteins, regulation of translation via small RNA interference, and alternative splicing events, among many others.

This Collection welcomes submissions covering updates and advancements in better understanding mechanisms of post-transcriptional regulation, as well as the impact of misregulation in the context of disease and evolution.

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Meet the Guest Editors

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Marco Mangone, PhD, Arizona State University, USA

Dr Mangone studies how eukaryotic RNA transcription is terminated and how the messenger RNA is regulated on its way to the expression into proteins, using the wound worm C. elegans as a model system. His research combines high-throughput genomics, bioinformatics, genetics, biochemistry, and systems biology and focuses on the characterization of 3' Untranslated Regions, and alternative polyadenylation events, with the ultimate goal of identifying cis-regulatory elements targeted by non-coding RNAs and proteins that bind and repress the translation of the mRNA into protein.

Gian Gaetano Tartaglia, PhD, Istituto Italiano di Tecnologia (IIT), Italy

Dr Tartaglia graduated from University La Sapienza, specializing in mathematical modeling of neurons, and later did his doctorate at the University of Zurich, which focused on protein folding related to neurodegenerative diseases. Subsequently, he delved into computational and experimental studies on amyloidosis at the University of Cambridge. As a PI at CRG Barcelona, Dr Tartaglia received an ERC grant in 2013 for research on RNA interactions with amyloid genes. Tenured as an ICREA professor in 2014, he became a Biochemistry professor at La Sapienza in 2018, joining IIT in 2019. His work, awarded an ERC grant in 2020, focuses on ribonucleoprotein interactions, elucidating their role in orchestrating post-transcriptional events and gene expression. Since September 2020, Dr Tartaglia is a Member of Academia Europaea (MAE).

About the Collection

BMC Biology is calling for submissions to our Collection on Regulation of gene expression through RNA. Forms of RNA-mediated regulation include the role of small RNAs in gene silencing, function modulation via RNA binding proteins, regulation of translation via small RNA interference, and alternative splicing events, among many others.

Post-transcriptional regulation mechanisms can affect adaptive divergence and evolution, and their misregulation can be at the center of disease onset and progression, making them suitable targets for therapeutic intervention.

This Collection welcomes submissions covering updates and advancements in better understanding mechanisms of post-transcriptional regulation, as well as the impact of misregulation in the context of disease and evolution.

Topics may include, but are not limited to:

Post-transcriptional events governing RNA stability and processing
Mechanisms of siRNAs and miRNAs in gene silencing
Impact of RNA binding proteins on gene expression
Post-transcriptional gene regulation by long non-coding RNAs
RNA-mediated gene regulation in disease and evolution
Therapeutic approaches targeting post-transcriptional regulation
RNA therapeutics

Image credit: [M] Artur Plawgo / Getty Images / iStock

There are currently no articles in this collection.

Submission Guidelines

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This Collection welcomes submission of original Research Articles.

Should you wish to submit a different article type, please read our submission guidelines to confirm that type is accepted by the journal.

To submit your manuscript to this Collection, please use our online submission system and indicate in your cover letter that you would like the article to be considered for inclusion in the "Regulation of gene expression through RNA" Collection.

Articles will undergo the journal’s standard peer-review process and are subject to all of the journal’s standard policies. Articles will be added to the Collection as they are published.

The Guest Editors have no competing interests with the submissions which they handle through the peer review process. The peer review of any submissions for which the Guest Editors have competing interests is handled by another Editor or Editorial Board Member who has no competing interests.