Clinical Trials Day 2024: Trailblazers Among Us

New Content Item Clinical Trials Day, celebrated on May 20th, is an opportunity to recognize and show appreciation to clinical research professionals for their efforts in improving public health.

This year's theme celebrates the work of clinical research professionals as modern-day trailblazers and the engines that power the advancement of human health.

Join us in celebrating Clinical Trials Day 2024 with blogs, featured articles, and collections from BMC Trials.

Clinical Trials Research

Supported online self-management versus care as usual for symptoms of fatigue, pain and urgency/incontinence in adults with inflammatory bowel disease (IBD-BOOST): study protocol for a randomised controlled trial—an update to the published protocol

The unblinding of statisticians in clinical trials: commentary on Iflaifel et al., Trials 2023

A small clinical trial of vaporized cannabis for PTSD: suggestive results and directions for future study

The importance of NOT being Other: Time to address the invisibility of nuanced gender and sexuality in clinical trials

Letter in response to: “The importance of clinical importance when determining the target difference in sample size calculations”

The need for a new keyword — “Trial registry-metaresearch” — to track certain uses of clinical trial registry records

Evaluating the feasibility and preliminary efficacy of a Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS): an update to the protocol for a feasibility cluster-randomised controlled trial

Minimum important difference is minimally important in sample size calculations

Update to the study protocol Face Your Fears: Virtual reality-based cognitive behavioral therapy (VR-CBT) versus standard CBT for paranoid ideations in patients with schizophrenia spectrum disorders: a randomized clinical trial

Motivations for paediatric vaccine trial participation

Safety and feasibility of faecal microbiota transplant for major depressive disorder: study protocol for a pilot randomised controlled trial

Evaluating the feasibility of prolonged-release buprenorphine formulations as an alternative to daily opioid agonist therapy regardless of prior treatment adherence: a pilot study

The Geras virtual frailty rehabilitation program to build resilience in older adults with frailty during COVID-19: a randomized feasibility trial

The feasibility of team care for women seeking to plan a vaginal breech birth (OptiBreech 1): an observational implementation feasibility study in preparation for a pilot trial

OUTdoor Swimming as a nature-based Intervention for DEpression (OUTSIDE): study protocol for a feasibility randomised control trial comparing an outdoor swimming intervention to usual care for adults experiencing mild to moderate symptoms of depression

Pilot and feasibility studies: extending the conceptual framework

Recommendations for progression criteria during external randomised pilot trial design, conduct, analysis and reporting

Patient engagement in clinical trial design for rare neuromuscular disorders: impact on the DELIVER and ACHIEVE clinical trials

Opening up ideas: an advent calendar for patient and public engagement in clinical trials research

“The power imbalance was blown out the window”: developing and implementing creative workshops to enhance communication of statistics in patient and public involvement in clinical trials

Advancing patient-centered research practices in a pragmatic patient-level randomized clinical trial: A thematic analysis of stakeholder engagement in Emergency Medicine Palliative Care Access (EMPallA)

“I think there has to be a mutual respect for there to be value”: Evaluating patient engagement in a national clinical trial on de-implementation of low value care

Featured Blogs

Key takeaways from recent conference attendance

Clinical Trials Day is a day to recognize the dedication of researchers, the resilience of participants, and the impact of clinical trials on improving healthcare worldwide.

Clinical trial registration: past, present, and future

Checklist browser window on laptop screen

This post examines clinical trial registration, detailing its origins, current strengths and weaknesses, and a call to re-engage with the vital practice moving forward.

Celebrating the trailblazers of wellbeing in research

We take a look at five ISRCTN studies championing patient wellbeing, carer wellbeing and healthcare professional wellbeing.

Combatting youth mental health stigma with art

Prof. Ana Beato of Lusófona University Portugal discusses the WeARTolerance arts-based program to reduce mental-health-related stigma in young people.

Welcoming Submissions

Call for papers: The collection, analysis and reporting of adverse events in randomised controlled trials

Trials is inviting submission of manuscripts, long and short, including original research and education articles for best practice in the collection, analysis and reporting of adverse events in randomised controlled trials.

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